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A biologically adapted dose-escalation approach, demonstrated for 18F-FET-PET in brain tumors

Rickhey, Mark ; Koelbl, Oliver ; Eilles, Christoph ; Bogner, Ludwig


Assuming that regions with high tracer uptake can be interpreted as target for radiotherapy, (18)F-FET-PET-based "dose painting by numbers" applied to brain tumors is a feasible approach. The dose, and therefore potentially the chance of tumor control, can be enhanced. The proposed model can easily be transferred to other tracers and tumor entities.

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