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A biologically adapted dose-escalation approach, demonstrated for 18F-FET-PET in brain tumors

Rickhey, Mark, Koelbl, Oliver, Eilles, Christoph and Bogner, Ludwig (2008) A biologically adapted dose-escalation approach, demonstrated for 18F-FET-PET in brain tumors. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 184 (10), pp. 536-542.

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Abstract

Assuming that regions with high tracer uptake can be interpreted as target for radiotherapy, (18)F-FET-PET-based "dose painting by numbers" applied to brain tumors is a feasible approach. The dose, and therefore potentially the chance of tumor control, can be enhanced. The proposed model can easily be transferred to other tracers and tumor entities.


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Item type:Article
Date:2008
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
19016044PubMed ID
10.1007/s00066-008-1883-6DOI
Classification:
NotationType
AgedMESH
Brain Neoplasms/radiotherapyMESH
Feasibility StudiesMESH
FemaleMESH
Fluorine Radioisotopes/pharmacokineticsMESH
Glioblastoma/radiotherapyMESH
HumansMESH
Image Processing, Computer-AssistedMESH
MaleMESH
Middle AgedMESH
Monte Carlo MethodMESH
Positron-Emission Tomography/methodsMESH
Radiotherapy DosageMESH
Radiotherapy Planning, Computer-Assisted/methodsMESH
Tomography, X-Ray ComputedMESH
Tyrosine/pharmacokineticsMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29218
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