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Transcranial sonography: integration into target volume definition for glioblastoma multiforme

Vordermark, D. ; Becker, G. ; Flentje, M. ; Richter, S. ; Goerttler-Krauspe, I. ; Koelbl, O.


Addition of TCS tumor volume to the contrast-enhancing CT volume in postoperative radiotherapy planning for GBM increases the treated volume by a median factor of 1.5. Since a high frequency of marginal recurrences is reported from dose-escalation trials of this disease, TCS may complement established methods in PTV definition.

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