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Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias

Stummer, Walter, Reulen, Hanns-Jürgen, Meinel, Thomas, Pichlmeier, Uwe, Schumacher, Wiebke, Tonn, Jörg-Christian, Rohde, Veit, Oppel, Falk, Turowski, Bernd, Woiciechowsky, Christian, Franz, Kea and Pietsch, Torsten (2008) Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias. Neurosurgery 62 (3), 564-576; discussion.

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Abstract

Treatment bias was demonstrated regarding resection and second-line therapies. However, bias and imbalances were controllable in the cohorts available from the 5-aminolevulinic acid study so that the present data now provide Level 2b evidence (Oxford Centre for Evidence-based Medicine) that survival depends on complete resection of enhancing tumor in glioblastoma multiforme.


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Item type:Article
Date:2008
Additional Information (public):ALA-Glioma Study Group
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
19487874PubMed ID
10.1227/01.neu.0000317304.31579.17DOI
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Bias (Epidemiology)MESH
Brain Neoplasms/surgeryMESH
Disease-Free SurvivalMESH
FemaleMESH
Germany/epidemiologyMESH
Glioblastoma/surgeryMESH
HumansMESH
MaleMESH
Middle AgedMESH
Neoplasm Recurrence, Local/prevention & controlMESH
PrevalenceMESH
Reproducibility of ResultsMESH
Risk AssessmentMESH
Risk FactorsMESH
Sensitivity and SpecificityMESH
Survival AnalysisMESH
Survival RateMESH
Treatment OutcomeMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29254
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