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Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation

Schweizer, Daniel ; Voitier, I. ; Heier, A. ; Serno, Tim ; Goepferich, Achim ; et, al.



Abstract

The sustained and localized delivery of monoclonal antibodies has become highly relevant, because of the increasing number of investigated local delivery applications in recent years. As the local delivery of antibodies is associated with high technological hurdles, very few successful approaches have been reported in the literature so far. Alginate-based delivery systems were previously ...

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