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Number of items at this level: 137.

2022

Dorn, Christoph , Petroff, David, Kratzer, Alexander, Kees, Frieder, Kloft, Charlotte, Zeitlinger, Markus, Wrigge, Hermann and Simon, Philipp (2022) Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis. European Journal of Drug Metabolism and Pharmacokinetics 47, pp. 749-755.

Forster, Lisa and Pockes, Steffen (2022) Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution. Scientific Reports 12 (1).

Endres, Katharina Walburga Maria (2022) Wirkstoffkonzentrationsbestimmungen zur Therapieleitung der medikamentösen Behandlung kardiovaskulärer Erkrankungen bei psychiatrischen Patienten. PhD, Universität Regensburg.

2021

Mietzner, Raphael , Pawlak, Ramona, Tamm, Ernst R. , Goepferich, Achim , Fuchshofer, Rudolf and Breunig, Miriam (2021) Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma. Pharmaceuticals 15 (1), p. 18.

Lawrowska, Alexandra (2021) Nanoparticles for drug delivery to ocular neovascularizations. PhD, Universität Regensburg.

Höring, Carina , Conrad, Marcus, Söldner, Christian A. , Wang, Jinan , Sticht, Heinrich , Strasser, Andrea and Miao, Yinglong (2021) Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations. International Journal of Molecular Sciences 22 (18), pp. 1-21.

Seibel-Ehlert, Ulla , Plank, Nicole, Inoue, Asuka, Bernhardt, Guenther and Strasser, Andrea (2021) Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors. International Journal of Molecular Sciences 22 (18), pp. 1-33.

Breunig, Miriam , Sonntag, Tobias, Froemel, Franziska, Stamer, W. Daniel, Ohlmann, Andreas and Fuchshofer, Rudolf (2021) Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy. Pharmaceutics 2021 (13), p. 901. (Submitted)

Schlossmann, Jens , Majer, Michael and Prueschenk, Sally (2021) Loss of PKGIβ/IRAG1 Signaling Causes Anemia-Associated Splenomegaly. International Journal of Molecular Sciences 22 (5458), pp. 1-20.

Antoni, Frauke (2021) Design, Synthesis and Characterization of ABCG2 Inhibitors with a Focus on Water Solubility and Stability in Plasma. PhD, Universität Regensburg.

Wolfgarten, Eva Maria (2021) HPTLC, HPLC-UV und HPLC-MS Untersuchungen zur Isolierung, zum Fingerprint und zur Quantifizierung von Iridoid- und Phenylethanoidglykosiden in den Blättern von Plantago lanceolata L. PhD, Universität Regensburg.

Endres, Katharina, Schiller, Ernst and Haen, Ekkehard (2021) Antihypertensiva in der Psychiatrie. Der Nervenarzt 92, pp. 487-792.

2020

Kuck, Katrin, Jürgenliemk, Guido, Lipowicz, Bartosz and Heilmann, Jörg (2020) Sesquiterpenes from Myrrh and Their ICAM-1 Inhibitory Activity In Vitro. Molecules 26 (1), p. 42.

Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther and Pockes, Steffen (2020) NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports 10, p. 13288.

Schwarz, Mirjam (2020) Erstellung eines Hypotonie-Risikoscores und Validierung anhand einer retrospektiven Anwendungsbeobachtung an geriatrischen Patienten. PhD, Universität Regensburg.

Thalhauser, Stefanie and Breunig, Miriam (2020) Considerations for efficient surface functionalization of nanoparticles with a high molecular weight protein as targeting ligand. European Journal of Pharmaceutical Sciences 155 (105520). Fulltext not available.

Bartole, Edith, Grätz, Lukas, Littmann, Timo, Wifling, David , Seibel, Ulla, Buschauer, Armin and Bernhardt, Günther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors. Journal of Medicinal Chemistry 63 (10), pp. 5297-5311. Fulltext not available.

Maslanka Figueroa, Sara , Fleischmann, Daniel, Beck, Sebastian, Tauber, Philipp, Witzgall, Ralph, Schweda, Frank and Goepferich, Achim (2020) Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells. Advanced Science 7 (11), p. 1903204.

Dorn, Christoph , Schießer, Selina, Wulkersdorfer, Beatrix, Hitzenbichler, Florian, Kees, Martin G. and Zeitlinger, Markus (2020) Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration. Biomedical Chromatography 34, e4820.

Abstiens, Kathrin (2020) Heteromultivalent Nanoparticles for Selective Targeting of Renal Cells. PhD, Universität Regensburg.

Fleischmann, Daniel, Maslanka-Figueroa, Sara, Beck, Sebastian, Abstiens, Kathrin, Witzgall, Ralph, Schweda, Frank, Tauber, Philipp and Goepferich, Achim (2020) Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification. ACS Applied Materials & Interfaces 12 (31), pp. 34689-34702. Fulltext not available.

Spinnler, Katrin, von Krüchten, Lara, Konieczny, Adam, Schindler, Lisa, Bernhardt, Günther and Keller, Max (2020) An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling “Bioorthogonal” Peptide Conjugation. ACS Medicinal Chemistry Letters 11 (3), pp. 334-339. Fulltext not available.

Weber, Laura, Kuck, Katrin, Jürgenliemk, Guido, Heilmann, Jörg, Lipowicz, Bartosz and Vissiennon, Cica (2020) Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa. Biomolecules 10 (7), p. 1033. Fulltext not available.

Buschmann, Jonas, Seiler, Theresa, Bernhardt, Günther, Keller, Max and Wifling, David (2020) Argininamide-type neuropeptide Y Y1 receptor antagonists: the nature of Nω-carbamoyl substituents determines Y1R binding mode and affinity. RSC Medicinal Chemistry 11 (2), pp. 274-282. Fulltext not available.

Ullah, Sami, Beer, Ronny, Fuhr, Uwe, Taubert, Max , Zeitlinger, Markus, Kratzer, Alexander, Dorn, Christoph, Arshad, Usman, Kofler, Mario and Helbok, Raimund (2020) Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics. Neurocritical Care.

Thalhauser, Stefanie and Breunig, Miriam (2020) Considerations for efficient surface functionalization of nanoparticles with a high molecular weight protein as targeting ligand. European Journal of Pharmaceutical Sciences (155), p. 105520. Fulltext not available.

Bohley, Marilena S., Birch, Emily, Baumann, Felix J., Dillinger, Andrea E., Tamm, Ernst R. and Goepferich, Achim M. (2020) Design of dye and superparamagnetic iron oxide nanoparticle loaded lipid nanocapsules with dual detectability in vitro and in vivo. International Journal of Pharmaceutics 585, p. 119433. Fulltext not available.

Gruber, Corinna G., Pegoli, Andrea, Müller, Christoph, Grätz, Lukas, She, Xueke and Keller, Max (2020) Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry 11 (7), pp. 823-832. Fulltext not available.

Keller, Max, Mahuroof, Shahani A., Hong Yee, Vivyanne, Carpenter, Jessica, Schindler, Lisa, Littmann, Timo, Pegoli, Andrea, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter and Holliday, Nicholas D. (2020) Fluorescence Labeling of Neurotensin(8–13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity. ACS Medicinal Chemistry Letters 11 (1), pp. 16-22. Fulltext not available.

Biselli, Sabrina, Alencastre, Inês, Tropmann, Katharina, Erdmann, Daniela, Chen, Mengya, Littmann, Timo, Maia, André F. , Gomez-Lazaro, Maria, Tanaka, Miho, Ozawa, Takeaki, Keller, Max, Lamghari, Meriem, Buschauer, Armin and Bernhardt, Günther (2020) Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications. ACS Medicinal Chemistry Letters 11 (8), pp. 1521-1528. Fulltext not available.

Abdellatif, Ahmed , Hennig, Robert, Pollinger, Klaus, Tawfeek, Hesham, Goepferich, Achim and make_name_string expected hash reference (2020) Fluorescent Nanoparticles Coated with a Somatostatin Analogue Target Blood Monocyte for Efficient Leukaemia Treatment. Pharmaceutical Research 37 (11), p. 2017.

Sommer, Judith, Dorn, Christoph , Gäbele, Erwin, Bataille, Frauke, Freese, Kim, Seitz, Tatjana, Thasler, Wolfgang E., Büttner, Reinhard, Weiskirchen, Ralf , Bosserhoff, Anja and Hellerbrand, Claus (2020) Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury. Cells 9 (1), p. 248.

Apaolaza, P.S. , Busch, M., Asin-Prieto, E. , Peynshaert, K. , Rathod, R., Remaut, K., Dünker, N. and Göpferich, A. (2020) Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery: Evaluation of the surface properties and effect on their distribution. Experimental Eye Research 198, p. 108151. Fulltext not available.

Biswas, Siladitta, Kojonazarov, Baktybek, Hadzic, Stefan, Majer, Michael, Bajraktari, Ganimete, Novoyatleva, Tatyana, Ghofrani, Hossein Ardeschir, Grimminger, Friedrich, Seeger, Werner, Weissmann, Norbert, Schlossmann, Jens and Schermuly, Ralph Theo (2020) IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension. Cells 9 (10), p. 2280. Fulltext not available.

Yagati, Ajay Kumar , Behrent, Arne, Beck, Sebastian, Rink, Simone, Goepferich, Achim M., Min, Junhong , Lee, Min-Ho and Baeumner, Antje J. (2020) Laser-induced graphene interdigitated electrodes for label-free or nanolabel-enhanced highly sensitive capacitive aptamer-based biosensors. Biosensors and Bioelectronics 164, p. 112272. Fulltext not available.

Pontes de Sousa, Ingrid, Ferreira, Antônio Gilberto , Miller Crotti, Antônio Eduardo, Alves dos Santos, Raquel, Kiermaier, Josef, Kraus, Birgit, Heilmann, Jörg and Jacometti Cardoso Furtado, Niege Araçari (2020) New antifungal ent-labdane diterpenes against Candida glabrata produced by microbial transformation of ent-polyalthic acid. Bioorganic Chemistry 95, p. 103560. Fulltext not available.

Konieczny, Adam, Braun, Diana, Wifling, David , Bernhardt, Günther and Keller, Max (2020) Oligopeptides as Neuropeptide Y Y4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist. Journal of Medicinal Chemistry 63 (15), pp. 8198-8215. Fulltext not available.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf and Breunig, Miriam (2020) Presentation of HIV-1 Envelope Trimers on the Surface of Silicia Nanoparticles. Journal of Pharmaceutical Sciences 109, pp. 911-921. Fulltext not available.

Ehmann, L., Simon, P., Busse, D., Petroff, D., Dorn, Christoph , Huisinga, W., Dietrich, A., Zeitlinger, M., Wrigge, H. and Kloft, C. (2020) Risk of target non-attainment In obese compared to non-obese patients In Calculated linezolid therapy. Clinical Microbiology and Infection. Fulltext not available.

Thalhauser, Stefanie, Peterhoff, David, Wagner, Ralf and Breunig, Miriam (2020) Silica particles incorporated into PLGA-based in situ-forming implants exploit the dual advantage of sustained release and particulate delivery. European Journal of Pharmaceutics and Biopharmaceutics (156), pp. 1-10. Fulltext not available.

Stolwijk, Judith A., Mildner, Anne-Kathrin, Kade, Christian, Skiba, Michael, Bernhardt, Guenther, Buschauer, Armin, Huebner, Harald, Gmeiner, Peter and Wegener, Joachim (2020) Stepwise Dosing Protocol for Increased Throughput in Label-Free Impedance-Based GPCR Assays. Journal of Visualized Experiments (156). Fulltext not available.

2019

Silva Gracia, Margarete (2019) Verbesserung der Arzneimitteltherapiesicherheit von Antipsychotika und Beta-Adrenozeptor-Antagonisten durch Therapeutisches Drug Monitoring und Untersuchungen zu pharmakokinetischen Interaktionen. PhD, Universität Regensburg.

Maschauer, Simone, Ott, Julian J. , Bernhardt, Günther, Kuwert, Torsten, Keller, Max and Prante, Olaf (2019) 18F-labelled triazolyl-linked argininamides targeting the neuropeptide Y Y1R for PET Imaging of mammary carcinoma. Scientific Reports 9, p. 12990.

Schramm, Andrea, Schweda, Frank, Sequeira-Lopez, Maria Luisa S., Hofmann, Franz, Sandner, Peter and Schlossmann, Jens (2019) Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion. Frontiers in Pharmacology 2019 (10), p. 800.

Dorn, Christoph, Petroff, David, Neumann, Nancy, Kratzer, Alexander, El-Najjar, Nahed , Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus , Kees, Martin, Kees, Frieder, Wrigge, Hermann and Simon, Philipp (2019) Plasma and tissue pharmacokinetics of fosfomycin in morbidly obese and non-obese surgical patients: a controlled clinical trial. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Pegoli, Andrea, Wifling, David , Gruber, Corinna G., Xueke, She, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter and Keller, Max (2019) Conjugation of Short Peptides to Dibenzodiazepinone-Type
Muscarinic Acetylcholine Receptor Ligands Determines M2R
Selectivity.
Journal of Medicinal Chemistry 62, pp. 5358-5369. Fulltext not available.

Schindler, Lisa, Bernhardt, Günther and Keller, Max (2019) Modifications at Arg and Ile Give Neurotensin(8−13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS Medicinal Chemistry Letters 10 (6), pp. 960-965. Fulltext not available.

Pockes, Steffen, Wifling, David , Buschauer, Armin and Elz, Sigurd (2019) Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands †. ChemistryOpen 8 (3), pp. 285-297.

Schramm, Simon, Agnetta, Luca, Bermudez, Marcel, Gerwe, Hubert, Irmen, Matthias, Holze, Janine, Littmann, Timo, Wolber, Gerhard , Tränkle, Christian and Decker, Michael (2019) Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism. ChemMedChem 14 (14), pp. 1349-1358. Fulltext not available.

Wiegrebe, Wolfgang (2019) Adam and Eve's Origin According to Islam: A Response to Daud Abdul-Fattah Batchelor. Theology and Science 17 (4), pp. 455-468. Fulltext not available.

Łażewska, Dorota , Mogilski, Szczepan, Hagenow, Stefanie , Kuder, Kamil, Głuch-Lutwin, Monika , Siwek, Agata , Więcek, Małgorzata, Kaleta, Maria, Seibel, Ulla, Buschauer, Armin, Filipek, Barbara, Stark, Holger and Kieć-Kononowicz, Katarzyna (2019) Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands. Bioorganic & Medicinal Chemistry 27 (7), pp. 1254-1262. Fulltext not available.

Polykandriotis, Elias, Horch, Raymund E., Jost, Matthias, Arkudas, Andreas, Kees, Frieder and Schmitz, Marweh (2019) Can systemically administered antibiotics be detected in wound tissues and surfaces under negative pressure wound therapy? International Wound Journal 16 (2), pp. 503-510. Fulltext not available.

Kowalewski, Christoph, Haen, Ekkehard, Hiemke, Christoph, Ridders, Florian, Endres, Katharina, Gründer, Gerhard, Paulzen, Michael and Schoretsanitis, Georgios (2019) Cytochrome P450-mediated inhibition of venlafaxine metabolism by trimipramine. International Clinical Psychopharmacology 34 (5), pp. 241-246. Fulltext not available.

Dorn, Christoph , Kratzer, Alexander Ludwig, Schießer, Selina, Kees, Frieder , Wrigge, Hermann and Simon, Philipp (2019) Determination of total or free cefazolin and metronidazole in human plasma or interstitial fluid by HPLC-UV for pharmacokinetic studies in man. Journal of Chromatography B. Fulltext not available.

Agnetta, Luca, Bermudez, Marcel , Riefolo, Fabio , Matera, Carlo , Claro, Enrique , Messerer, Regina, Littmann, Timo, Wolber, Gerhard , Holzgrabe, Ulrike and Decker, Michael (2019) Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. Journal of Medicinal Chemistry 62 (6), pp. 3009-3020. Fulltext not available.

Graf, Moritz, Ziegler, Christian, Gregoritza, Manuel and Goepferich, Achim (2019) Hydrogel microspheres evading alveolar macrophages for sustained pulmonary protein delivery. nternational Journal of Pharmaceutics 566, pp. 652-661. Fulltext not available.

Scharrenbroich, Jessica, Kaever, Volkhard, Dove, Stefan, Seifert, Roland and Schneider, Erich H. (2019) Hydrolysis of the non-canonical cyclic nucleotide cUMP by PDE9A: kinetics and binding mode. Naunyn-Schmiedeberg's Archives of Pharmacology 392 (2), pp. 199-208. Fulltext not available.

Walz, Johanna M., Wecker, Thomas , Zhang, Pei Pei, Cakir, Bertan, Gruening, Bjoern, Agostini, Hansjuergen, Reuer, Tristan, Ludwig, Franziska, Boneva, Stefaniya , Faerber, Lothar, Lange, Clemens, Schlunck, Guenther R. and Stahl, Andreas (2019) Impact of angiogenic activation and inhibition on miRNA profiles of human retinal endothelial cells. Experimental Eye Research 181, pp. 98-104. Fulltext not available.

Stolwijk, J. A., Skiba, M., Kade, C., Bernhardt, G., Buschauer, Armin , Hübner, H., Gmeiner, P. and Wegener, Joachim (2019) Increasing the throughput of label-free cell assays to study the activation of G-protein-coupled receptors by using a serial agonist exposure protocol. Integrative Biology 11 (3), pp. 99-108. Fulltext not available.

Maslanka-Figueroa, Sara, Veser, Anika, Abstiens, Kathrin, Fleischmann, Daniel and Göpferich, Achim (2019) Influenza A virus mimetic nanoparticles trigger selective cell uptake. PNAS 116 (20), pp. 9831-9836. Fulltext not available.

Gergs, U. , Bernhardt, Günther, Buchwalow, I. B., Edler, H., Fröba, J., Keller, Max, Kirchhefer, U., Köhler, F., Mißlinger, N., Wache, H. and Neumann, J. (2019) Initial Characterization of Transgenic Mice Overexpressing Human Histamine H2 Receptors. Journal of Pharmacology and Experimental Therapeutics 369 (1), pp. 129-141. Fulltext not available.

Abstiens, Kathrin , Maslanka Figueroa, Sara , Gregoritza, Manuel and Göpferich, Achim (2019) Interaction of funtionalized nanoparticles with serum proteins and its impact on colloidal stability and cargo leaching. Soft Matter 15 (4), pp. 709-720. Fulltext not available.

Bohley, Marilena, Haunberger, Alexandra and Göpferich, Achim (2019) Intracellular availability of poorly soluble drugs from lipid nanocapsules. European Journal of Pharmaceutics and Biopharmaceutics 139, pp. 23-32. Fulltext not available.

Abstiens, Kathrin and Göpferich, Achim (2019) Microfluidic manufacturing improves polydispersity of multicomponent polymeric nanoparticles. Journal of Drug Delivery Science and Technology 49, pp. 433-439. Fulltext not available.

Schoretsanitis, Georgios , Haen, Ekkehard, Hiemke, Christoph, Endres, Katharina, Ridders, Florian, Veselinovic, Tanja, Gründer, Gerhard and Paulzen, Michael (2019) Pharmacokinetic correlates of venlafaxine: associated adverse reactions. European Archives of Psychiatry and Clinical Neuroscience 269 (7), pp. 851-857. Fulltext not available.

Heider, Fabian , Ansideri, Francesco, Tesch, Roberta, Pantsar, Tatu, Haun, Urs, Döring, Eva, Kudolo, Mark, Poso, Antti , Albrecht, Wolfgang, Laufer, Stefan A. and Koch, Pierre (2019) Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors. European Journal of Medicinal Chemistry 175, pp. 309-329. Fulltext not available.

Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Oesterreicher, Zoe Anne, Dorn, Christoph, Adamzik, Michael, Kees, Frieder, Zeitlinger, Markus and Rahmel, Tim (2019) Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients. Journal of Antimicrobial Chemotherapy. Fulltext not available.

Schwindl, Sebastian, Kraus, Birgit and Heilmann, Jörg (2019) Secondary metabolites from the leaves of Juglans regia L. Biochemical Systematics and Ecology 83, pp. 130-136. Fulltext not available.

Kerres, Sabine, Plut, Eva, Malcherek, Simon, Rehbein, Julia and Reiser, Oliver (2019) Visible Light‐Mediated Synthesis of Enantiopure γ‐Cyclobutane Amino and 3‐(Aminomethyl)‐5‐phenylpentanoic Acids. Advanced Synthesis & Catalysis 361 (6), pp. 1400-1407. Fulltext not available.

2018

Abstiens, Kathrin , Gregoritza, Manuel and Goepferich, Achim (2018) Ligand Density and Linker Length are Critical Factors for Multivalent Nanoparticle−Receptor Interactions. ACS Applied Materials & Interfaces 11 (1), pp. 1311-1320. Fulltext not available.

Kratzer, Alexander, Schießer, Selina, Matzneller, Peter, Wulkersdorfer, Beatrix, Zeitlinger, Markus , Schlossmann, Jens , Kees, Frieder and Dorn, Christoph (2018) Determination of Total and Free Ceftolozane and Tazobactam in Human Plasma and Interstitial Fluid by HPLC-UV. Journal of Pharmaceutical and Biomedical Analysis. Fulltext not available.

Walz, Johanna Madeleine (2018) VEGF-Inhibition bei der Frühgeborenenretinopathie
- Präklinische und klinische Aspekte -.
PhD, Universität Regensburg.

Böhr, Sebastian (2018) Therapeutisches Drug Monitoring der direkten oralen Antikoagulanzien. PhD, Universität Regensburg.

Dukorn, Stefanie (2018) Pharmacological tools for the NPY receptors: [³⁵S]GTPγS binding assays, luciferase gene reporter assays and labeled peptides. PhD, Universität Regensburg.

Dietrich, Peter, Kuphal, Silke, Spruss, Thilo, Hellerbrand, Claus and Bosserhoff, Anja K. (2018) Micro RNA ‐622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma. Pigment Cell & Melanoma Research 31 (5), pp. 614-629. Fulltext not available.

Walz, J. M., Bemme, S., Reichl, S., Akman, S., Breuß, H., Süsskind, D., Glitz, B., Müller, V. C., Wagenfeld, L., Gabel-Pfisterer, A., Aisenbrey, S., Engelmann, K., Koutsonas, A., Krohne, T. U. and Stahl, A. (2018) Behandelte Frühgeborenenretinopathie in Deutschland. Der Ophthalmologe 115 (6), pp. 476-488. Fulltext not available.

Leonhardt, Michel, Sellmer, Andreas , Krämer, Oliver H., Dove, Stefan, Elz, Sigurd, Kraus, Birgit, Beyer, Mandy and Mahboobi, Siavosh (2018) Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors. European Journal of Medicinal Chemistry 152, pp. 329-357. Fulltext not available.

Ridinger, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Koerholz, Katharina, Mahboobi, Siavosh, Hellweg, Lars, Gunkel, Nikolas, Miller, Aubry K., Peterziel, Heike, Schmezer, Peter, Hamacher-Brady, Anne , Witt, Olaf and Oehme, Ina (2018) Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance. Scientific Reports 8 (1). Fulltext not available.

Gregoritza, Manuel, Abstiens, Kathrin , Graf, Moritz and Göpferich, Achim (2018) Fabrication of antibody-​loaded microgels using microfluidics and thiol-​ene photoclick chemistry. European Journal of Pharmaceutics and Biopharmaceutics 127, pp. 194-203. Fulltext not available.

Dorn, Christoph, Kratzer, Alexander, Liebchen, Uwe, Schleibinger, Michael, Murschhauser, Alexandra, Schlossmann, Jens , Kees, Frieder, Simon, Philipp and Kees, Martin G. (2018) Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration. Journal of Pharmaceutical Sciences 107 (2), pp. 739-744. Fulltext not available.

Wiesneth, Stefan, Aas, Gregor, Heilmann, Jörg and Jürgenliemk, Guido (2018) Investigation of the flavan-3-ol patterns in willow species during one growing-season. Phytochemistry 145, pp. 26-39. Fulltext not available.

Sellmer, Andreas, Stangl, Hubert, Beyer, Mandy, Grünstein, Elisabeth, Leonhardt, Michel, Pongratz, Herwig, Eichhorn, Emerich, Elz, Sigurd, Striegl, Birgit, Jenei-Lanzl, Zsuzsa, Dove, Stefan, Straub, Rainer H., Krämer, Oliver H. and Mahboobi, Siavosh (2018) Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors. Journal of Medicinal Chemistry 61 (8), pp. 3454-3477. Fulltext not available.

Schoretsanitis, Georgios, de Leon, Jose, Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2018) Pharmacokinetics of risperidone in different application forms – Comparing long-acting injectable and oral formulations. European Neuropsychopharmacology 28 (1), pp. 130-137. Fulltext not available.

Mathioudaki, Angeliki, Berzesta, Ariola, Kypriotakis, Zacharias, Skaltsa, Helen and Heilmann, Jörg (2018) Phenolic metabolites from Hypericum kelleri Bald., an endemic species of Crete (Greece). Phytochemistry 146, pp. 1-7. Fulltext not available.

Peña-Solórzano, Diana, Scholler, Matthias, Bernhardt, Günther, Buschauer, Armin , König, Burkhard and Ochoa-Puentes, Cristian (2018) Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators. ACS Medicinal Chemistry Letters 9, pp. 854-859. Fulltext not available.

Dietrich, P., Kuphal, S., Spruss, T., Hellerbrand, C. and Bosserhoff, A. K. (2018) Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition. Oncogene 37 (7), pp. 897-911. Fulltext not available.

2017

Chen, Kang, Berg, Nele, Gschwind, Ruth Maria and König, Burkhard (2017) Selective Single C(sp3)−F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation. Journal of the American Chemical Society 139, pp. 18444-18447. Fulltext not available.

She, Xueke, Pegoli, Andrea, Mayr, Judith, Hübner, Harald, Bernhardt, Günther , Gmeiner, Peter and Keller, Max (2017) Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity. ACS Omega 2 (10), pp. 6741-6754.

Dukorn, Stefanie, Littmann, Timo, Keller, Max, Kuhn, Kilian K., Cabrele, Chiara , Baumeister, Paul, Bernhardt, Günther and Buschauer, Armin (2017) Fluorescence- and radio-labeling of Lys4,Nle17,30hPP yields molecular tools for the NPY Y4 receptor. Bioconjugate Chemistry. Fulltext not available.

Noack, Katrin, Mahendrarajah, Nisintha, Hennig, Dorle, Schmidt, Luisa, Grebien, Florian , Hildebrand, Dagmar, Christmann, Markus, Kaina, Bernd, Sellmer, Andreas, Mahboobi, Siavosh, Kubatzky, Katharina, Heinzel, Thorsten and Krämer, Oliver H. (2017) Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells. Archives of Toxicology 91 (5), pp. 2191-2208. Fulltext not available.

Mayr, Judith, Bachl, Jürgen, Schlossmann, Jens and Díaz Díaz, David (2017) Antimicrobial and Hemolytic Studies of a Series of Polycations Bearing Quaternary Ammonium Moieties: Structural and Topological Effects. International Journal of Molecular Sciences 18, p. 303.

Schäfer, Claudia, Göder, Anja, Beyer, Mandy, Kiweler, Nicole, Mahendrarajah, Nisintha, Rauch, Anke, Nikolova, Teodora, Stojanovic, Natasa, Wieczorek, Martin, Reich, Thomas R., Tomicic, Maja T., Linnebacher, Michael, Sonnemann, Jürgen, Dietrich, Sascha, Sellmer, Andreas, Mahboobi, Siavosh, Heinzel, Thorsten, Schneider, Günter and Krämer, Oliver H. (2017) Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells. Cellular Signalling 29, pp. 218-225. Fulltext not available.

Wittmann, Hans-Joachim and Strasser, Andrea (2017) Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions? Naunyn-Schmiedeberg's Archives of Pharmacology 390 (6), pp. 595-612. Fulltext not available.

Gregoritza, Manuel , Messmann, Viktoria, Abstiens, Kathrin, Brandl, Ferdinand and Göpferich, Achim (2017) Controlled Antibody Release from Degradable Thermoresponsive
Hydrogels Cross-Linked by Diels−Alder Chemistry.
Biomacromolecules 18, pp. 2410-2418. Fulltext not available.

Schoretsanitis, Georgios , Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard and Paulzen, Michael (2017) Effect of smoking on risperidone pharmacokinetics – A multifactorial approach to better predict the influence on drug metabolism. Schizophrenia Research 185, pp. 51-57. Fulltext not available.

Mahendrarajah, Nisintha, Borisova, Marina E., Reichardt, Sigrid, Godmann, Maren, Sellmer, Andreas, Mahboobi, Siavosh, Haitel, Andrea, Schmid, Katharina, Kenner, Lukas , Heinzel, Thorsten, Beli, Petra and Krämer, Oliver H. (2017) HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3. Cellular Signalling 39, pp. 9-17. Fulltext not available.

Kuhn, Kilian K., Littmann, Timo, Dukorn, Stefanie, Tanaka, Miho, Keller, Max, Ozawa, Takeaki, Bernhardt, Günther and Buschauer, Armin (2017) In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists. ACS Omega 2 (7), pp. 3616-3631.

Pegoli, Andrea , She, Xueke, Wifling, David , Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter and Keller, Max (2017) Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor. Journal of Medicinal Chemistry 60 (8), pp. 3314-3334. Fulltext not available.

2016

Onuoha, Mary Remigius Agatha (2016) Therapeutic Drug Monitoring of Antipsychotics - HPLC Analytical Method Development and Pharmaceutical Advices to the Ward Clinicians - For Successful Individualized Therapy. PhD, Universität Regensburg.

Lieb, Sebastian (2016) Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods. PhD, Universität Regensburg.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki and Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, pp. 13-26. Fulltext not available.

Töpper, Christoph, Steinbach, Cathérine Louise, Dorn, Christoph , Kratzer, Alexander, Wicha, Sebastian G., Schleibinger, Michael, Liebchen, Uwe, Kees, Frieder, Salzberger, Bernd and Kees, Martin G. (2016) Variable linezolid exposure in ICU patients—possible role of drug-drug interactions. Therapeutic Drug Monitoring 38 (5), pp. 573-578. Fulltext not available.

Kunath, Julia (2016) Designermoleküle hemmen die Semaphorin 3F Wirkung in vitro, haben aber keinen Einfluss auf den Verlauf der experimentellen Arthritis. PhD, Universität Regensburg.

Schlossmann, Jens, Wetzl, Veronika, Schinner, Elisabeth, Kees, Frieder K., Hofmann, Franz and Faerber, Lothar (2016) Involvement of cyclic guanosine monophosphate-dependent protein kinase I in renal antifibrotic effects of serelaxin. Frontiers in Pharmacology 7 (195), pp. 1-27.

Hennig, Robert (2016) Multivalent nanoparticles for the treatment of ocular diseases. PhD, Universität Regensburg.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver and Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), pp. 6045-6058. Fulltext not available.

Limmer, Franziska (2016) Funktionelle Analyse der cGMP-abhängigen Proteinkinase I in der Niere, insbesondere im dicken aufsteigenden Ast der Henle-Schleife. PhD, Universität Regensburg.

Stangl, Hubert Werner (2016) Arthritis and cholinergic transition of sympathetic nerve fibers. PhD, Universität Regensburg.

Vögeler, Jessica (2016) Pharmakotherapie und Humanpharmakologische Untersuchungen bei Patienten mit DME (Diabetisches Makulaödem) und PDR (Proliferative Diabetische Retinopathie) anhand klinischer Parameter und inflammatorischer Biomarker. PhD, Universität Regensburg.

Lorenz, Peter, Knittel, Diana N., Conrad, Jürgen, Lotter, Eva M., Heilmann, Jörg, Stintzing, Florian C. and Kammerer, Dietmar R. (2016) 1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: Lipid Compounds fromEuphrasia rostkovianaHayneandE. tetraquetra(Bréb.)Arrond. Chemistry & Biodiversity 13 (5), pp. 602-612. Fulltext not available.

Hammer, Sebastian, Gobleder, Susanne, Naporra, Franziska, Wittmann, Hans-Joachim, Elz, Sigurd, Heinrich, Markus and Strasser, Andrea (2016) 2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity. Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300. Fulltext not available.

Hennig, Robert, Kuespert, Sabrina, Haunberger, Alexandra, Goepferich, Achim and Fuchshofer, Rudolf (2016) Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis. Journal of Drug Targeting 24 (10), pp. 952-959. Fulltext not available.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim M. and Brandl, Ferdinand P. (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels–Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), pp. 3398-3408. Fulltext not available.

Sawatzky, Edgar, Wehle, Sarah, Kling, Beata, Wendrich, Jan, Bringmann, Gerhard, Sotriffer, Christoph A., Heilmann, Jörg and Decker, Michael (2016) Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode. Journal of Medicinal Chemistry 59 (5), pp. 2067-2082. Fulltext not available.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine , Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara , Vanderheyden, Patrick, Gmeiner, Peter and Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), pp. 1925-1945. Fulltext not available.

Khan, Nadia, Saad, Ali, Nurulain, Syed M., Darras, Fouad H., Decker, Michael and Sadek, Bassem (2016) The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. Behavioural Brain Research 297, pp. 155-164. Fulltext not available.

Huang, Guozheng , Schramm, Simon, Heilmann, Jörg, Biedermann, David, Křen, Vladimír and Decker, Michael (2016) Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins. Beilstein Journal of Organic Chemistry 12, pp. 662-669. Fulltext not available.

2015

Mahli, Abdo (2015) Novel in vitro model for combined effects of alcohol and free fatty acids on hepatocellular lipid accumulation and inflammation. PhD, Universität Regensburg.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios , Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea and Decker, Michael (2015) Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders. ChemMedChem 11 (12), pp. 1270-1283. Fulltext not available.

2014

Thiele, Karinna Marie (2014) Charakterisierung Gαi3-gendefizienter Mauslinien. PhD, Universität Regensburg.

2013

Brandl, Katharina (2013) Erratum: Untersuchungen zur pharmakologischen Beeinflussung der Toll-like Rezeptoren in der Sepsis.

2012

Wagner, Eva (2012) Synthese und pharmakologische Charakterisierung dualer Histamin-H1-/H4-Rezeptorliganden. PhD, Universität Regensburg.

2011

Wagner, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2011) Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R. Bioorganic & Medicinal Chemistry Letters 21, pp. 6274-9280. Fulltext not available.

2009

Silva, Maria Elena (2009) Theoretical study of the interaction of agonists with the 5-HT2A receptor. PhD, Universität Regensburg.

2008

Egger, M., Pellett, P., Nickl, K., Geiger, S., Graetz, S., Seifert, R., Heilmann, J. and König, B. (2008) Synthesis and Cannabinoid Receptor Activity of Ketoalkenes from Echinacea pallida and Non-natural Analogues. Chem. Eur. J. 14, 10978 - 10984. Fulltext not available.

2007

Matzdorf, Corina (2007) Untersuchungen zur Rolle von Cyclooxygenase-2-gebildeten Prostaglandinen für die Bildung und Freisetzung von Renin. PhD, Universität Regensburg.

Schlegel, Birgit, Laggner, Christian, Meier, Rene, Langer, Thierry, Schnell, David, Seifert, Roland, Stark, Holger, Höltje, Hans-Dieter and Sippl, Wolfgang (2007) Generation of a homology model of the human histamine H₃ receptor for ligand docking and pharmacophore-based screening. Journal of Computer-Aided Molecular Design.

2006

Lotter, Kristina (2006) Anti-inflammatorische Eigenschaften von Makrolid-Antibiotika bei akuter Lipopolysaccharid-induzierter Entzündung. PhD, Universität Regensburg.

Reithmeier-Rost, Dagmar (2006) Immunmodulation durch Interaktion des Yersinia enterocolitica V-Antigens mit Rezeptoren des angeborenen Immunsystems. PhD, Universität Regensburg.

2005

Brandl, Katharina (2005) Untersuchungen zur pharmakologischen Beeinflussung der Toll-like Rezeptoren in der Sepsis. PhD, Universität Regensburg.

2004

Lyssenko, Alexei (2004) Synthese der Alkaloide Botryllazin B und (4-Hydroxyphenyl)-[4-(4-hydroxyphenyl)-1H-imidazol-2-yl]methanon sowie Synthese von Brevicollinderivaten. PhD, Universität Regensburg.

2003

Ladenburger, Stephan (2003) Relevanz der Galenik am Beispiel des Critical Dose Pharmakons Ciclosporin: Untersuchungen zur Pharmakokinetik und Pharmakodynamik verschiedener galenischer Formulierungen an gesunden Probanden und Ratten. PhD, Universität Regensburg.

Schneider, Dietmar (2003) Ringschluß- / Ringöffnungsreaktionen von Pyridinen: Synthese von N-Heterocyclen und Untersuchung auf Zytotoxizität. PhD, Universität Regensburg.

Jehkul, Andreas (2003) Klinisch-pharmakologische Untersuchungen zur Pharmakodynamik und Pharmakokinetik von Codein und Propyphenazon an Probanden und Patienten. PhD, Universität Regensburg.

2002

Dreher, Franziska (2002) Pharmakologische, molekularbiologische und biochemische Untersuchungen zur Beeinflussung des Renin-Angiotensin-Systems und der renalen Cyclooxygenase- und NO-Synthase-Isoenzyme in der Frühphase der primären, genetisch bedingten und sekundären, Immunsuppressivainduzierten Hypertonie. PhD, Universität Regensburg.

Bürgermeister, Jutta (2002) Wirkmechanistische Untersuchungen antiangiogener Galactansulfate. PhD, Universität Regensburg.

Köhler, Jens (2002) Untersuchungen zur Pharmakokinetik und Pharmakodynamik verschiedener galenischer Formulierungen des Immunsuppressivums Cyclosporin A vor und nach Nierentranplantation an Ratten. PhD, Universität Regensburg.

This list was generated on Thu Sep 29 20:36:30 2022 CEST.
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