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Rechallenge with temozolomide in patients with recurrent gliomas

Wick, Antje, Pascher, Christina, Wick, Wolfgang, Jauch, Tanja, Weller, Michael, Bogdahn, Ulrich and Hau, Peter (2009) Rechallenge with temozolomide in patients with recurrent gliomas. Journal of neurology 256 (5), pp. 734-741.

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Abstract

Temozolomide (TMZ) is the standard of care for patients with newly diagnosed glioblastoma (GBM) as well as those with recurrent anaplastic glioma (AG) and GBM. It has become common practice to re-expose patients to TMZ who had been previously treated with TMZ, or to switch patients to alternative dosing regimens of TMZ when there are signs of relapse or progress on standard TMZ therapeutic ...

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Item type:Article
Date:2009
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
19240962PubMed ID
10.1007/s00415-009-5006-9DOI
Classification:
NotationType
AdultMESH
AgedMESH
Antineoplastic Agents, Alkylating/adverse effectsMESH
Brain/physiopathologyMESH
Brain Neoplasms/physiopathologyMESH
Cohort StudiesMESH
Dacarbazine/analogs & derivativesMESH
Disease ProgressionMESH
Disease-Free SurvivalMESH
Dose-Response Relationship, DrugMESH
Drug Administration ScheduleMESH
Drug Resistance, Neoplasm/physiologyMESH
FemaleMESH
Glioma/physiopathologyMESH
HumansMESH
MaleMESH
Middle AgedMESH
Neoplasm Recurrence, Local/physiopathologyMESH
Retrospective StudiesMESH
Treatment OutcomeMESH
Young AdultMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29310
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