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Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors

Rivera, Francisco J., Kandasamy, Mahesh, Couillard-Despres, Sebastien, Caioni, Massimiliano, Sanchez, Rosario, Huber, Christophe, Weidner, Norbert, Bogdahn, Ulrich and Aigner, Ludwig (2008) Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors. Journal of neurochemistry 107 (3), pp. 832-843.

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Abstract

The oligodendrogenic program of progenitor cells in the adult CNS follows a sequential process of progenitor proliferation, fate choice, determination, differentiation, maturation and survival. Previously, we described a soluble activity derived from mesenchymal stem cells that induces oligodendrogenesis in adult neural progenitor cells. Here, we hypothesized that ciliary neurotrophic factor ...

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Item type:Article
Date:2008
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
18786165PubMed ID
10.1111/j.1471-4159.2008.05674.xDOI
Classification:
NotationType
Adult Stem Cells/physiologyMESH
AnimalsMESH
Cell DeathMESH
Cell Differentiation/physiologyMESH
Cell ProliferationMESH
Ciliary Neurotrophic Factor/metabolismMESH
Culture Media, ConditionedMESH
Fluorescent Antibody TechniqueMESH
Hippocampus/metabolismMESH
ImmunoblottingMESH
Mesenchymal Stromal Cells/physiologyMESH
Oligodendroglia/physiologyMESH
RatsMESH
Reverse Transcriptase Polymerase Chain ReactionMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29316
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