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CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors

Beier, Dagmar, Wischhusen, Jörg, Dietmaier, Wolfgang, Hau, Peter, Proescholdt, Martin A., Brawanski, Alexander, Bogdahn, Ulrich and Beier, Christoph P. (2008) CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors. Brain pathology 18 (3), pp. 370-377.

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Abstract

High-grade oligodendroglial tumors, that is, anaplastic oligodendroglial tumors and glioblastomas with oligodendroglial component, differ significantly in terms of prognosis and response to chemotherapy. Differentiation might be difficult because the histological differences are vague and reliable markers are not established. We correlated the presence of putative cancer stem cells (CSC) in ...

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Item type:Article
Date:2008
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
18371181PubMed ID
10.1111/j.1750-3639.2008.00130.xDOI
Classification:
NotationType
Antigens, CD/biosynthesisMESH
Brain Neoplasms/pathologyMESH
Flow CytometryMESH
Glioma/pathologyMESH
Glycoproteins/biosynthesisMESH
HumansMESH
ImmunohistochemistryMESH
Neoplastic Stem Cells/metabolismMESH
Oligonucleotide Array Sequence AnalysisMESH
PeptidesMESH
PrognosisMESH
Tumor Markers, Biological/analysisMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29319
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