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CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors

Beier, Dagmar ; Wischhusen, Jörg ; Dietmaier, Wolfgang ; Hau, Peter ; Proescholdt, Martin A. ; Brawanski, Alexander ; Bogdahn, Ulrich ; Beier, Christoph P.



Abstract

High-grade oligodendroglial tumors, that is, anaplastic oligodendroglial tumors and glioblastomas with oligodendroglial component, differ significantly in terms of prognosis and response to chemotherapy. Differentiation might be difficult because the histological differences are vague and reliable markers are not established. We correlated the presence of putative cancer stem cells (CSC) in ...

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