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Adult medulloblastoma: prognostic factors and response to therapy at diagnosis and at relapse

Herrlinger, Ulrich ; Steinbrecher, A. ; Rieger, J. ; Hau, Peter ; Kortmann, R.-D. ; Meyermann, R. ; Schabet, M. ; Bamberg, M. ; Dichgans, J. ; Bogdahn, U. ; Weller, M.


Adult medulloblastoma is a rare tumor with few retrospective studies published so far. The role of adjuvant chemotherapy or chemotherapy at relapse is unclear. This study reports therapy and outcome in all adult (>or=16 years old) medulloblastoma (n=34) and supratentorial primitive neuroectodermal tumor (PNET) patients (n=2) treated in 2 neuro-oncological centers between 1976 and 2002. The median ...


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