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Salvage therapy in patients with glioblastoma: is there any benefit?

Hau, Peter ; Baumgart, Ulrike ; Pfeifer, Katharina ; Bock, Anne ; Jauch, Tanya ; Dietrich, Jörg ; Fabel, Klaus ; Grauer, Oliver ; Wismeth, Caecilia ; Klinkhammer-Schalke, Monika ; Allgäuer, Michael ; Schuierer, Gerhard ; Koch, Horst ; Schlaier, Juergen ; Ulrich, Winfried ; Brawanski, Alexander ; Bogdahn, Ulrich ; Steinbrecher, Andreas



Abstract

BACKGROUND. Survival after first-line therapy is poor for patients with glioblastoma. The role of second-line treatment for recurrent disease is controversial. The authors studied the outcome in a subset of patients with glioblastoma who were selected for an aggressive reintervention strategy at the time of progression. Their objectives were to improve patients' overall survival with sustained ...

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