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Salvage therapy in patients with glioblastoma: is there any benefit?

Hau, Peter ; Baumgart, Ulrike ; Pfeifer, Katharina ; Bock, Anne ; Jauch, Tanya ; Dietrich, Jörg ; Fabel, Klaus ; Grauer, Oliver ; Wismeth, Caecilia ; Klinkhammer-Schalke, Monika ; Allgäuer, Michael ; Schuierer, Gerhard ; Koch, Horst ; Schlaier, Juergen ; Ulrich, Winfried ; Brawanski, Alexander ; Bogdahn, Ulrich ; Steinbrecher, Andreas


The majority of patients in the current series were treated with a reintervention strategy, which had an impact on PFS and mOS. A second resection, focal radiotherapy (in selected cases), and additional chemotherapeutic regimens should be considered for patients with recurrent glioblastoma.

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