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Advances in the therapy of high-grade glioma at relapse: pegylated liposomal doxorubicin

Hau, Peter ; Dietrich, Joerg ; Fabel, Klaus ; Bogdahn, Ulrich



Abstract

Approaches to improve the prognosis of patients with high-grade glioma, which is still grim despite combined therapy and major advances in the development of new drugs, are highly important. Chemotherapeutic agents have not consistently produced favorable results in the relapse setting so far, with tumor responses reported in a minority of cases. Among them, doxorubicin has not shown significant ...

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