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Long-term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin

Fabel, K. ; Dietrich, J. ; Hau, Peter ; Wismeth, C. ; Winner, B. ; Przywara, S. ; Steinbrecher, A. ; Ullrich, W. ; Bogdahn, U.



Abstract

Doxorubicin has been shown to be a safe treatment with moderate activity that may lead to long-term stabilization in recurrent high-grade glioma patients. Of note, median OS after all and after initiation of recurrence therapy was prolonged in comparison with the OS in other Phase II studies, as recently described by Wong et al. (Wong ET, Hess KR, Gleason MJ, Jaeckle KA, Kyritsis AP, Prados MD, ...

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