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Investigation of the 1H NMR visibility of lactate in different rat and human brain cells

Kotitschke, K., Schnackerz, K. D., Dringen, R., Bogdahn, U., Haase, A. and von Kienlin, M. (1994) Investigation of the 1H NMR visibility of lactate in different rat and human brain cells. NMR in biomedicine 7 (8), pp. 349-355.

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Abstract

In recent years, 1H MRS has been used in a number of studies to measure the lactate content of brain, and it is generally assumed that the methyl resonance at 1.3 ppm reflects the total amount of lactate present in the tissue. However, reduced NMR visibility of lactate has recently been reported for blood, heart and skeletal muscle as well as for bacteria. We have assessed the NMR visibility of ...

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Item type:Article
Date:1994
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
7742202PubMed ID
Classification:
NotationType
AnimalsMESH
Astrocytes/chemistryMESH
Brain/cytologyMESH
Brain Chemistry/physiologyMESH
Cells, CulturedMESH
HumansMESH
Lactates/analysisMESH
Lactic AcidMESH
Magnetic Resonance SpectroscopyMESH
Neuroglia/chemistryMESH
ProtonsMESH
RatsMESH
Tumor Cells, CulturedMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29379
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