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In vitro studies on interaction of 4-hydroperoxy-ifosfamide and radiotherapy in malignant gliomas

Jäger, A. H., Bogdahn, U., Pfeufer, B., Richter, J., Apfel, R. and Dekant, A. (1993) In vitro studies on interaction of 4-hydroperoxy-ifosfamide and radiotherapy in malignant gliomas. Anticancer research 13 (6A), pp. 2221-2227.

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Abstract

Drug-radiation multimodal chemotherapy for malignant brain tumor cells was stimulated in vitro by a recently developed computer program, based on evaluation of 3D-response surfaces and interaction isoboles. Three malignant glioma tumor cell cultures (HTZ17, 146 and 209 B) were sequentially treated in vitro by increasing doses of 4-hydroperoxy-ifosfamide, according to in vivo/in vitro ...

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Item type:Article
Date:1993
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
8297137PubMed ID
Classification:
NotationType
AstrocytomaMESH
Cell Survival/radiation effectsMESH
Cobalt RadioisotopesMESH
Combined Modality Therapy/methodsMESH
Dose-Response Relationship, DrugMESH
Gamma RaysMESH
GlioblastomaMESH
Glioma/therapyMESH
HumansMESH
Ifosfamide/toxicityMESH
KineticsMESH
MathematicsMESH
Models, TheoreticalMESH
Tumor Cells, CulturedMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29383
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