Go to content
UR Home

Interleukin-2 and blood brain barrier in cats: pharmacokinetics and tolerance following intrathecal and intravenous administration

Martin, R., Schwuléra, U., Menke, G., Rudolph, W., Buch, K., Fasold, H., Lissner, R., Thrun, A., Krauseneck, P. and Bogdahn, U. (1992) Interleukin-2 and blood brain barrier in cats: pharmacokinetics and tolerance following intrathecal and intravenous administration. European cytokine network 3 (4), pp. 399-406.

Full text not available from this repository.

at PubMed


Abstract

Single bolus doses of glycosylated human interleukin-2 (n IL-2) in the range of 2.8 x 10(3) to 2.0 x 10(6) IU/kg were administered to anesthesized cats via the cephalic vein (n = 10) or using suboccipital puncture (n = 8). CSF (cerebrospinal fluid) and blood samples were collected by repeated puncture. The n IL-2 concentration in four cats was determined on the basis of its biologic activity ...

plus


Export bibliographical data



Item type:Article
Date:1992
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
1421012PubMed ID
Classification:
NotationType
AnimalsMESH
Blood-Brain Barrier/physiologyMESH
CatsMESH
Drug StabilityMESH
Drug ToleranceMESH
FemaleMESH
Injections, IntravenousMESH
Injections, SpinalMESH
Interleukin-2/pharmacokineticsMESH
MaleMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29388
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons