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MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation

Delic, Sabit, Lottmann, Nadine, Stelzl, Anja, Liesenberg, Franziska, Wolter, Marietta, Götze, Silke, Zapatka, Marc, Shiio, Yuzuru, Sabel, Michael C., Felsberg, Jörg, Reifenberger, Guido and Riemenschneider, Markus J. (2014) MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation. Neuro-Oncology 16 (2), pp. 179-190.

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Abstract

Background: Diffusely infiltrative growth of human astrocytic gliomas is one of the major obstacles to successful tumor therapy. Thorough insights into the molecules and pathways signaling glioma cell invasion thus appear of major relevance for the development of targeted and individualized therapies. By miRNA expression profiling of microdissected human tumor biopsy specimens we identified ...

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Item type:Article
Date:2014
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
10.1093/neuonc/not164DOI
Keywords:astrocytoma, brain tumor, epigenetic, glioblastoma, miRNA
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29403
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