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5-FU-induced cardiac toxicity - an underestimated
problem in radiooncology?

URN to cite this document:
urn:nbn:de:bvb:355-epub-295104
Steger, Felix ; Hautmann, Matthias ; Koelbl, Oliver
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Date of publication of this fulltext: 12 Feb 2014 10:38


Abstract

Background 5-Fluorouracil (5-FU) is an antimetabolite, which is frequently used as chemotherapeutic agent for combined chemoradiotherapy. The purpose of this study was to present the clinical course of three patients who developed severe cardiac toxicity by 5-FU and to give a review of the literature on the cardiotoxic potential of 5-FU. Results Cardiotoxicity is a rare, but relevant side ...

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