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IL-13 signaling via IL-13Ralpha2 triggers TGF-beta1-dependent allograft fibrosis

Brunner, Stefan, Schichl, Gabriela, Kesselring, Rebecca, Martin, Maria, Balam, Saido, Schlitt, Hans-Jürgen, Geissler, Edward K. and Fichtner-Feigl, Stefan (2013) IL-13 signaling via IL-13Ralpha2 triggers TGF-beta1-dependent allograft fibrosis. Transplantation Research 2, p. 16.

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Date of publication of this fulltext: 12 Feb 2014 11:45

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Abstract

Background Allograft fibrosis still remains a critical problem in transplantation, including heart transplantation. The IL-13/TGF-β1 interaction has previously been identified as a key pathway orchestrating fibrosis in different inflammatory immune disorders. Here we investigate if this pathway is also responsible for allograft fibrosis and if interference with the IL-13/TGF-β1 interaction ...

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Item type:Article
Date:22 October 2013
Institutions:Medicine > Lehrstuhl für Chirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/2047-1440-2-16DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29517
Owner only: item control page

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