| License: Creative Commons: Attribution 3.0 PDF - Published Version (2MB) |
- URN to cite this document:
- urn:nbn:de:bvb:355-epub-295199
- DOI to cite this document:
- 10.5283/epub.29519
Alternative links to fulltext:DOI
Abstract
Background: CD137 and its ligand (CD137L) are potent immunoregulatory molecules that influence activation, proliferation, differentiation and cell death of leukocytes. Expression of CD137 is upregulated in the lamina propria cells of Crohn's disease patients. Here, the role of CD137 in acute Dextran-Sodium-Sulfate (DSS)-induced colitis in mice was examined. Methods: We induced acute large bowel ...

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