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CD137 Facilitates the Resolution of Acute DSS-Induced Colonic Inflammation in Mice

Martinez Gomez, Julia M., Lieping, Chen, Schwarz, Herbert and Karrasch, Thomas (2013) CD137 Facilitates the Resolution of Acute DSS-Induced Colonic Inflammation in Mice. PLoS ONE 8 (9).

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Date of publication of this fulltext: 12 Feb 2014 11:57

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Abstract

Abstract Background CD137 and its ligand (CD137L) are potent immunoregulatory molecules that influence activation, proliferation, differentiation and cell death of leukocytes. Expression of CD137 is upregulated in the lamina propria cells of Crohn’s disease patients. Here, the role of CD137 in acute Dextran-Sodium-Sulfate (DSS)-induced colitis in mice was examined. Methods We induced acute ...

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Item type:Article
Date:2013
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0073277DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29519
Owner only: item control page

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