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Molecular profiling of single Sca-1+/CD34+,- cells - the putative murine lung stem cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-295251
Hittinger, Markus ; Zbigniew, Czyz T. ; Huesemann, Yves ; Maneck, Matthias ; Botteron, Catherine ; Kaeufl, Stephanie ; Klein, Christoph A. ; Polzer, Bernhard
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Date of publication of this fulltext: 12 Feb 2014 12:23


Abstract

Murine bronchioalveolar stem cells play a key role in pulmonary epithelial maintenance and repair but their molecular profile is poorly described so far. In this study, we used antibodies directed against Sca-1 and CD34, two markers originally ascribed to pulmonary cells harboring regenerative potential, to isolate single putative stem cells from murine lung tissue. The mean detection rate of ...

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