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The prognostic value of Her4 receptor isoform expression in triple-negative and Her2 positive breast cancer patients

URN to cite this document:
urn:nbn:de:bvb:355-epub-295268
Machleidt, Anna ; Buchholz, Stefan ; Diermeier-Daucher, S ; Zeman, Florian ; Ortmann, Olaf ; Brockhoff, Gero
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Date of publication of this fulltext: 12 Feb 2014 12:26


Abstract

Background Not only four but rather seven different humane pidermal growth factor receptor related (Her) receptor tyrosine kinases (RTKs) have been described to be expressed in a variety of normal and neoplastic tissues: Her1, Her2, Her3, and additionally four Her4 isoforms have been identified. A differential expression of Her4 isoforms does not, however, play any role in either the molecular ...

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