Go to content
UR Home

Adipose tissue-derived Stem Cell (ASC) secreted IGF-1 protects myoblasts from the negative effect of Myostatin

URN to cite this document:
urn:nbn:de:bvb:355-epub-295339
Gehmert, Sebastian ; Wenzel, Carina ; Loibl, Markus ; Brockhoff, Gero ; Huber, Michaela ; Krutsch, Werner ; Nerlich, Michael ; Gosau, Martin ; Klein, Silvan ; Schreml, Stephan ; Prantl, Lukas ; Gehmert, Sanga
[img]
Preview
License: Creative Commons Attribution 3.0
PDF - Published Version
(3MB)
Date of publication of this fulltext: 12 Feb 2014 12:41


Abstract

Myostatin, a TGF-β family member, is associated with inhibition of muscle growth and differentiation and might interact with the IGF-1 signaling pathway. Since IGF-1 is secreted at a bioactive level by adipose tissue-derived mesenchymal stem cells (ASCs), these cells (ASCs) provide a therapeutic option for Duchenne Muscular Dystrophy (DMD). But the protective effect of stem cell secreted IGF-1 on ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons