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Comparative proteomic profiles of meningioma subtypes

Okamoto, H. ; Li, J. ; Vortmeyer, A. O. ; Jaffe, H. ; Lee, Y. S. ; Glasker, S. ; Sohn, T. S. ; Zeng, W. ; Ikejiri, B. ; Proescholdt, M. A. ; Mayer, C. ; Weil, R. J. ; Oldfield, E. H. ; Zhuang, Z.



Abstract

Meningiomas are classified into three groups (benign, atypical, and anaplastic) based on morphologic characteristics. Atypical meningiomas, which are WHO grade 2 tumors, and anaplastic meningiomas, which are WHO grade 3 tumors, exhibit an increased risk of recurrence and premature death compared with benign WHO grade 1 tumors. Although atypical and anaplastic meningiomas account for <10% of all ...

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