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Monocyte to Macrophage Differentiation Goes along with Modulation of the Plasmalogen Pattern through Transcriptional Regulation

Wallner, Stefan, Grandl, Margot, Konovalova, Tatiana, Sigrüner, Alexander, Kopf, Thomas, Peer, Markus, Orsó, Evelyn, Liebisch, Gerhard and Schmitz, Gerd (2014) Monocyte to Macrophage Differentiation Goes along with Modulation of the Plasmalogen Pattern through Transcriptional Regulation. PLoS ONE.

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Date of publication of this fulltext: 17 Apr 2014 11:07

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Other URL: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0094102


Abstract

Dysregulation of monocyte-macrophage differentiation is a hallmark of vascular and metabolic diseases and associated with persistent low grade inflammation. Plasmalogens represent ether lipids that play a role in diabesity and previous data show diminished plasmalogen levels in obese subjects. We therefore analyzed transcriptomic and lipidomic changes during monocyte-macrophage differentiation in vitro using a bioinformatic approach.


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Item type:Article
Date:8 April 2014
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0094102DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29826
Owner only: item control page

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