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Stable immunosuppression under low-dose Tacrolimus monotherapy is dependent upon immunological regulation

Kammler, Anja Nadine (2015) Stable immunosuppression under low-dose Tacrolimus monotherapy is dependent upon immunological regulation. PhD, Universität Regensburg.

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Date of publication of this fulltext: 27 May 2015 16:44

Abstract (English)

Allograft acceptance in solid organ transplantation might not be determined by mechanisms unique to the tolerant state but rather by the balance between the effector and regulatory immune response. In consequence, this quantitative view of tolerance implies the existence of marginal states, wherein regulatory responses are just insufficient to prevent rejection, or in which regulatory responses ...

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Translation of the abstract (German)

Die Akzeptanz eines Transplantats wird möglicherweise nicht durch einzigartige Toleranzmechanismen bestimmt, sondern vielmehr durch die Bilanz aus der Effektorantwort und der regulatorischen Immunantwort. Diese quantitative Ansicht der Toleranz umfasst auch die Existenz von Grenzfällen, wobei die regulatorische Immunantwort gerade nicht ausreicht, um die Transplantasabstoßung zu verhindern; oder ...

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Export bibliographical data



Item type:Thesis of the University of Regensburg (PhD)
Date:27 May 2015
Referee:Prof. Dr. Edward K. Geissler
Date of exam:21 May 2014
Institutions:Medicine > Lehrstuhl für Chirurgie
Keywords:immunsuppression, regulation, Tacrolimus, mouse model, skin transplantation, transplantation
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30096
Owner only: item control page

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