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Molecular analysis of plasmalemma vesicle-associated protein and its biological functions in the mammalian vascular endothelium

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Herrnberger, Leonie
Date of publication of this fulltext: 04 Aug 2015 15:48

Abstract (English)

Plasmalemma vesicle-associated protein (PLVAP), a cationic, endothelial-specific, integral membrane glycoprotein is exclusively localized to stomatal and fenestral diaphragms of caveolae, transendothelial channels and fenestrae. Fenestral and stomatal diaphragms are known to consist of radial fibrils which extend from the peripheral rim of the celllular pore and meet in a central mesh. They act ...


Translation of the abstract (German)

Plasmalemma Vesicle-Associated Protein (PLVAP), ein kationisches integrales Membranglykoprotein ist spezifisch in stomatalen und fenestralen Diaphragmen von Caveolae, transendothelialen Kanälen und Fenestrae exprimiert. Fenestrale und stomatale Diaphragmen bestehen aus radiären Fibrillen, welche am Rand der zellulären Pore verankert sind und sich von dort ausgehend in einem zentralen Knoten ...


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