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The Natural Chemopreventive Agent Sulforaphane Inhibits STAT5 Activity

Prinz, Sophia, Unser, Samy and Rascle, Anne (2014) The Natural Chemopreventive Agent Sulforaphane Inhibits STAT5 Activity. PLoS ONE 9 (6), e99391.

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Date of publication of this fulltext: 09 Jul 2014 12:09

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Other URL: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0099391


Abstract

Signal transducer and activator of transcription STAT5 is an essential mediator of cytokine, growth factor and hormone signaling. While its activity is tightly regulated in normal cells, its constitutive activation directly contributes to oncogenesis and is associated to a number of hematological and solid tumor cancers. We previously showed that deacetylase inhibitors can inhibit STAT5 ...

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Item type:Article
Date:9 June 2014
Institutions:Medicine > Lehrstuhl für Immunologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0099391DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30401
Owner only: item control page

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