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Quantitative Measurement of Melanoma Spread in Sentinel Lymph Nodes and Survival

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Ulmer, Anja ; Dietz, Klaus ; Hodak, Isabelle ; Polzer, Bernhard ; Scheitler, Sebastian ; Yildiz, Murat ; Czyz, Zbigniew ; Lehnert, Petra ; Fehm, Tanja ; Hafner, Christian ; Schanz, Stefan ; Röcken, Martin ; Garbe, Claus ; Breuning, Helmut ; Fierlbeck, Gerhard ; Klein, Christoph A.
Date of publication of this fulltext: 21 Jul 2014 11:54


Background Sentinel lymph node spread is a crucial factor in melanoma outcome. We aimed to define the impact of minimal cancer spread and of increasing numbers of disseminated cancer cells on melanoma-specific survival. Methods and Findings We analyzed 1,834 sentinel nodes from 1,027 patients with ultrasound node-negative melanoma who underwent sentinel node biopsy between February 8, 2000, and ...


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