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Icb-1 gene polymorphism rs1467465 is associated with susceptibility to ovarian cancer

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Schüler, Susanne ; Lattrich, Claus ; Skrzypczak, Maciej ; Fehm, Tanja ; Ortmann, Olaf ; Treeck, Oliver
Date of publication of this fulltext: 04 Aug 2014 09:15


In this study, we tested the hypothesis that single nucleotide polymorphisms (SNPs) of differentiation-associated human gene icb-1 (C1orf38) may be associated with ovarian cancer susceptibility. For this purpose, we compared the genotype and allele frequencies of the SNPs rs1467465 and rs12048235 in a group of 184 ovarian cancer patients with a control group of 184 age- and gender-matched women ...


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