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Are applied growth factors able to mimic the positive effects of mesenchymal stem cells on the regeneration of meniscus in the avascular zone?

Zellner, Johannes, Taeger, Christian Dirk, Schaffer, Markus, Roldan, J. Camilo, Loibl, Markus, Müller, Michael, Berner, Arne, Krutsch, Werner, Huber, Michaela, Kujat, Richard, Nerlich, Michael and Angele, Peter (2014) Are applied growth factors able to mimic the positive effects of mesenchymal stem cells on the regeneration of meniscus in the avascular zone? BioMed Research International.

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Date of publication of this fulltext: 20 Aug 2014 05:09

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Other URL: http://www.hindawi.com/journals/bmri/aip/537686/


Abstract

(PRP) or Bone Morphogenic Protein 7 (BMP7) are in the focus of interest. In this study the effects of PRP and BMP7 on the regeneration of avascular meniscal defects were evaluated. In vitro analysis showed that PRP secretes multiple growth factors over a period of 8 days. BMP7 enhances the collagen II deposition in an aggregate culture model of MSCs. However applied to different shaped meniscal ...

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Item type:Article
Date:18 August 2014
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1155/2014/537686DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30695
Owner only: item control page

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