Are applied growth factors able to mimic the positive effects of mesenchymal stem cells on the regeneration of meniscus in the avascular zone?

URN to cite this document:: urn:nbn:de:bvb:355-epub-306950
DOI to cite this document:: 10.5283/epub.30695

Zellner, Johannes ; Taeger, Christian Dirk ; Schaffer, Markus ; Roldan, J. Camilo ; Loibl, Markus

; Müller, Michael ; Berner, Arne ; Krutsch, Werner ; Huber, Michaela ; Kujat, Richard ; Nerlich, Michael ; Angele, Peter

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Date of publication of this fulltext: 20 Aug 2014 05:09

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Abstract

Meniscal lesions in the avascular zone are still a problem in traumatology. Tissue Engineering approaches with mesenchymal stem cells (MSCs) showed successful regeneration of meniscal defects in the avascular zone. However in daily clinical practice a single stage regenerative treatment would be preferable for meniscus injuries. In particular clinically applicable bioactive substances or isolated ...