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Influence of Fenofibrate treatment on triacylglycerides diacylglycerides and fatty acids in fructose fed rats

Kopf, Thomas, Schaefer, Hans-Ludwig, Troetsmueller, Martin, Koefeler, Harald, Broenstrup, Mark, Konovalova, Tatiana and Schmitz, Gerd (2014) Influence of Fenofibrate treatment on triacylglycerides diacylglycerides and fatty acids in fructose fed rats. PLoS ONE 9 (9), e106849.

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Date of publication of this fulltext: 11 Sep 2014 13:30

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Other URL: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0106849


Abstract

Fenofibrate (FF) lowers plasma triglycerides via PPARα activation. Here, we analyzed lipidomic changes upon FF treatment of fructose fed rats. Three groups with 6 animals each were defined as control, fructose-fed and fructose-fed/FF treated. Male Wistar Unilever Rats were subjected to 10% fructose-feeding for 20 days. On day 14, fenofibrate treatment (100 mg/kg p.o.) was initiated and maintained ...

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Item type:Article
Date:8 September 2014
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0106849DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30744
Owner only: item control page

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