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Vesicular aptasensor for the detection of thrombin

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Müller, Andreas ; König, Burkhard
License: Creative Commons Attribution 3.0
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Date of publication of this fulltext: 30 Sep 2014 12:02


Self-assembled phospholipid vesicles are functionalized with thrombinbinding aptamers using a thiol-click reaction. The resulting aptasensors signal the binding of the analyte to the vesicle surface by changes of the emission properties of membrane co-embedded reporter dyes.

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