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Biochemical characterization of photoactivated adenylyl cyclase from Naegleria gruberi

Tanwar, Meenakshi ; Stierl, Manuela ; Veetil, Sindhu Kandoth ; Penzkofer, Alfons ; Hegemann, Peter ; Kateriya, Suneel


Abstract

Blue light sensors using FAD (BLUF) domains are flavin based blue light photoreceptors. The BLUF domains are often fused with various effector domains. BLUF domain coupled with adenylyl cyclase domain is known as photoactivated adenylyl cyclase (PAC). Naegleria gruberi genome database analysis revealed the presence of four PACs. Each of the photoactivated adenylyl cyclases from Naegleria gruberi ...

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