Experimental Heart Failure Induces Alterations of the Lung Proteome - Insight into Molecular Mechanisms - University of Regensburg Publication Server

URN to cite this document:: urn:nbn:de:bvb:355-epub-308502
DOI to cite this document:: 10.5283/epub.30850

Birner, Christoph ; Hierl, S. ; Dietl, A. ; Hupf, J. ; Jungbauer, C. ; Schmid, Peter M. ; Rümmele, Petra ; Deutzmann, Rainer ; Riegger, Günter A. J. ; Luchner, A.

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Date of publication of this fulltext: 06 Oct 2014 10:32

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Abstract

Background: Heart failure (CHF) is characterized by dyspnea and pulmonary changes. The underlying molecular adaptations are unclear, but might provide targets for therapeutic interventions. We therefore conceived a study to determine molecular changes of early pulmonary stress failure in a model of tachycardia-induced heart failure. Methods: CHF was induced in rabbits by progessive right ...