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Reninexpression in der Angiotensin II-AT1a-Rezeptor- und Connexin 40- Doppel-Knockout-Maus

Müller, Hanna (2014) Reninexpression in der Angiotensin II-AT1a-Rezeptor- und Connexin 40- Doppel-Knockout-Maus. PhD, Universität Regensburg.

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Date of publication of this fulltext: 16 Oct 2014 11:44

Abstract (German)

In dieser Arbeit sollten die Auswirkungen des kombinierten Knockouts von Cx40 und dem AT1a-Rezeptor auf die Reninexpression, auf die physiologischen Regulationsmechanismen der Reninexpression und auf die Architektur des renal arteriellen Gefäßsystems beleuchtet werden. Hierzu wurden Nierenserienschnitte von Wildtyp-, AT1a-KO-, Cx40-KO- und AT1a-Cx40-DOKO-Mäusen angefertigt und gegen Renin und ...

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Translation of the abstract (English)

In this work, the effects of combined knockouts of Cx40 and the AT1a receptor should be illuminated on the renin expression in the physiological regulation mechanisms of renin expression and the architecture of the renal arterial vasculature. For this purpose, kidney serial sections of wild-type, AT1a-KO, Cx40-KO and AT1a-Cx40-DOKO mice were prepared and stained for renin and smooth muscle actin. ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:16 October 2014
Referee:Prof. Armin Kurtz
Date of exam:13 October 2014
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Keywords:Connexin 40, Angiotensin II-AT1a-Rezeptor, Doppelknockout, Renin-Angiotensin-Aldosteron-System
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30874
Owner only: item control page

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