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Staphylococcus aureus Gene Expression in a Rat Model of Infective Endocarditis

URN to cite this document:
urn:nbn:de:bvb:355-epub-309319
Hanses, Frank ; Roux, Christelle M. ; Dunman, Paul M. ; Salzberger, Bernd ; Lee, Jean C.
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Date of publication of this fulltext: 04 Nov 2014 17:15


Abstract

BackgroundDiabetes mellitus is a frequent underlying comorbidity in patients with Staphylococcus aureus endocarditis, and it represents a risk factor for complications and a negative outcome. The pathogenesis of staphylococcal endocardial infections in diabetic hosts has been poorly characterized, and little is known about S. aureus gene expression in endocardial vegetations.MethodsWe utilized a ...

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