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Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant
Apfelbacher, Christian J., Drewitz, Karl Philipp, Loss, Martin und Loss, Julika
(2014)
Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant.
BMC Health Services Research 14 (584).
Veröffentlichungsdatum dieses Volltextes: 05 Dez 2014 14:32
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.31022
Zusammenfassung
Background: The majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany. Methods: Routine Eurotransplant data of 3,666 deceased German donors (from 2002-2011) were used for ...
Background: The majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany. Methods: Routine Eurotransplant data of 3,666 deceased German donors (from 2002-2011) were used for multivariate modelling. Socio-demographic and medical factors were considered as independent variables in logistic regression models with non-transplantation as dependent variable. Results: Male gender, advanced age, overweight/obesity, long ICU stay, a history of smoking, non-traumatic brain death, elevated levels of sodium, serum glucose, lipase/amylase and the liver not being considered for procurement were significant independent predictors of non-transplantation. Conclusion: In line with previous research, advanced age, high BMI, long ICU stay and the liver not being considered for procurement were the strongest predictors of pancreas non-transplantation in Germany. About three quarters of the variance remained unexplained, suggesting that factors not assessed or unknown may play a decisive role.
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| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | BMC Health Services Research | ||||
| Verlag: | BIOMED CENTRAL LTD | ||||
|---|---|---|---|---|---|
| Ort der Veröffentlichung: | LONDON | ||||
| Band: | 14 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 584 | ||||
| Datum | 25 November 2014 | ||||
| Institutionen | Medizin > Lehrstuhl für Chirurgie Medizin > Institut für Epidemiologie und Präventivmedizin > Medizinische Soziologie | ||||
| Identifikationsnummer |
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| Stichwörter / Keywords | PANCREAS TRANSPLANTATION; DECISION-MAKING; KIDNEY; SURGEONS; MORTALITY; ACCEPT; Pancreas transplantation; Donor factors; Donor organ allocation | ||||
| Dewey-Dezimal-Klassifikation | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| URN der UB Regensburg | urn:nbn:de:bvb:355-epub-310226 | ||||
| Dokumenten-ID | 31022 |
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