Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant

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urn:nbn:de:bvb:355-epub-310226 Copy

Apfelbacher, Christian J. ; Drewitz, Karl Philipp ; Loss, Martin ; Loss, Julika

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Date of publication of this fulltext: 05 Dec 2014 14:32

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Details

Item type:	Article
Journal or Publication Title:	BMC Health Services Research
Publisher:	BioMed Central
Volume:	14
Number of Issue or Book Chapter:	584
Date:	25 November 2014
Institutions:	Medicine > Institut für Epidemiologie und Präventivmedizin
Projects:	Open Access Publizieren (DFG)
Identification Number:	Value Type 10.1186/s12913-014-0584-3 DOI
Keywords:	Pancreas transplantation, Donor factors, Donor organ allocation
Dewey Decimal Classification:	600 Technology > 610 Medical sciences Medicine
Status:	Published
Refereed:	Yes, this version has been refereed
Created at the University of Regensburg:	Yes
Item ID:	31022

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Abstract

BackgroundThe majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany.MethodsRoutine Eurotransplant data of 3,666 deceased German donors (from 2002?2011) were used for ...

Abstract

BackgroundThe majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany.MethodsRoutine Eurotransplant data of 3,666 deceased German donors (from 2002?2011) were used for multivariate modelling. Socio-demographic and medical factors were considered as independent variables in logistic regression models with non-transplantation as dependent variable.ResultsMale gender, advanced age, overweight/obesity, long ICU stay, a history of smoking, non-traumatic brain death, elevated levels of sodium, serum glucose, lipase/amylase and the liver not being considered for procurement were significant independent predictors of non-transplantation.ConclusionIn line with previous research, advanced age, high BMI, long ICU stay and the liver not being considered for procurement were the strongest predictors of pancreas non-transplantation in Germany. About three quarters of the variance remained unexplained, suggesting that factors not assessed or unknown may play a decisive role.

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Metadata last modified: 02 Jun 2018 06:31

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