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Apfelbacher, Christian J. ; Drewitz, Karl Philipp ; Loss, Martin ; Loss, Julika

Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant

Apfelbacher, Christian J., Drewitz, Karl Philipp, Loss, Martin und Loss, Julika (2014) Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant. BMC Health Services Research 14 (584).

Veröffentlichungsdatum dieses Volltextes: 05 Dez 2014 14:32
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.31022


Zusammenfassung

Background: The majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany. Methods: Routine Eurotransplant data of 3,666 deceased German donors (from 2002-2011) were used for ...

Background: The majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany. Methods: Routine Eurotransplant data of 3,666 deceased German donors (from 2002-2011) were used for multivariate modelling. Socio-demographic and medical factors were considered as independent variables in logistic regression models with non-transplantation as dependent variable. Results: Male gender, advanced age, overweight/obesity, long ICU stay, a history of smoking, non-traumatic brain death, elevated levels of sodium, serum glucose, lipase/amylase and the liver not being considered for procurement were significant independent predictors of non-transplantation. Conclusion: In line with previous research, advanced age, high BMI, long ICU stay and the liver not being considered for procurement were the strongest predictors of pancreas non-transplantation in Germany. About three quarters of the variance remained unexplained, suggesting that factors not assessed or unknown may play a decisive role.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftBMC Health Services Research
Verlag:BIOMED CENTRAL LTD
Ort der Veröffentlichung:LONDON
Band:14
Nummer des Zeitschriftenheftes oder des Kapitels:584
Datum25 November 2014
InstitutionenMedizin > Lehrstuhl für Chirurgie
Medizin > Institut für Epidemiologie und Präventivmedizin > Medizinische Soziologie
Identifikationsnummer
WertTyp
10.1186/s12913-014-0584-3DOI
Stichwörter / KeywordsPANCREAS TRANSPLANTATION; DECISION-MAKING; KIDNEY; SURGEONS; MORTALITY; ACCEPT; Pancreas transplantation; Donor factors; Donor organ allocation
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-310226
Dokumenten-ID31022

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