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Faltermeier, Rupert ; Bele, Sylvia ; Proescholdt, Martin A. ; Brawanski, Alexander

Windowed multi taper correlation analysis of multimodal brain monitoring parameters

Faltermeier, Rupert, Bele, Sylvia, Proescholdt, Martin A. and Brawanski, Alexander (2015) Windowed multi taper correlation analysis of multimodal brain monitoring parameters. Computational and Mathematical Methods in Medicine 2015, pp. 1-8.

Date of publication of this fulltext: 19 Feb 2015 13:07
Article
DOI to cite this document: 10.5283/epub.31353


Abstract

Although multimodal monitoring sets the standard in daily practice of neurocritical care, problem-oriented analysis tools to interpret the huge amount of data are lacking. Recently a mathematical model was presented that simulates the cerebral perfusion and oxygen supply in case of a severe head trauma, predicting the appearance of distinct correlations between arterial blood pressure and ...

Although multimodal monitoring sets the standard in daily practice of neurocritical care, problem-oriented analysis tools to interpret the huge amount of data are lacking. Recently a mathematical model was presented that simulates the cerebral perfusion and oxygen supply in case of a severe head trauma, predicting the appearance of distinct correlations between arterial blood pressure and intracranial pressure. In this study we present a set of mathematical tools that reliably detect the predicted correlations in data recorded at a neurocritical care unit. The time resolved correlations will be identified by a windowing technique combined with Fourier-based coherence calculations. The phasing of the data is detected by means of Hilbert phase difference within the above mentioned windows. A statistical testing method is introduced that allows tuning the parameters of the windowing method in such a way that a predefined accuracy is reached. With this method the data of fifteen patients were examined in which we found the predicted correlation in each patient. Additionally it could be shown that the occurrence of a distinct correlation parameter, called scp, represents a predictive value of high quality for the patients outcome.



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Details

Item typeArticle
Journal or Publication TitleComputational and Mathematical Methods in Medicine
Publisher:HINDAWI PUBLISHING CORPORATION
Place of Publication:NEW YORK
Volume:2015
Page Range:pp. 1-8
Date16 February 2015
InstitutionsMedicine > Lehrstuhl für Neurochirurgie
Identification Number
ValueType
10.1155/2015/124325DOI
Article ID 124325Other
KeywordsINTENSIVE-CARE-UNIT; ANEURYSMAL SUBARACHNOID HEMORRHAGE; SEVERE HEAD-INJURY; NEUROCRITICAL CARE; INTRACRANIAL-PRESSURE; MICRODIALYSIS;
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-313532
Item ID31353

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