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Faltermeier, Rupert ; Bele, Sylvia ; Proescholdt, Martin A. ; Brawanski, Alexander

Windowed multi taper correlation analysis of multimodal brain monitoring parameters

Faltermeier, Rupert, Bele, Sylvia, Proescholdt, Martin A. und Brawanski, Alexander (2015) Windowed multi taper correlation analysis of multimodal brain monitoring parameters. Computational and Mathematical Methods in Medicine 2015, S. 1-8.

Veröffentlichungsdatum dieses Volltextes: 19 Feb 2015 13:07
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.31353


Zusammenfassung

Although multimodal monitoring sets the standard in daily practice of neurocritical care, problem-oriented analysis tools to interpret the huge amount of data are lacking. Recently a mathematical model was presented that simulates the cerebral perfusion and oxygen supply in case of a severe head trauma, predicting the appearance of distinct correlations between arterial blood pressure and ...

Although multimodal monitoring sets the standard in daily practice of neurocritical care, problem-oriented analysis tools to interpret the huge amount of data are lacking. Recently a mathematical model was presented that simulates the cerebral perfusion and oxygen supply in case of a severe head trauma, predicting the appearance of distinct correlations between arterial blood pressure and intracranial pressure. In this study we present a set of mathematical tools that reliably detect the predicted correlations in data recorded at a neurocritical care unit. The time resolved correlations will be identified by a windowing technique combined with Fourier-based coherence calculations. The phasing of the data is detected by means of Hilbert phase difference within the above mentioned windows. A statistical testing method is introduced that allows tuning the parameters of the windowing method in such a way that a predefined accuracy is reached. With this method the data of fifteen patients were examined in which we found the predicted correlation in each patient. Additionally it could be shown that the occurrence of a distinct correlation parameter, called scp, represents a predictive value of high quality for the patients outcome.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftComputational and Mathematical Methods in Medicine
Verlag:HINDAWI PUBLISHING CORPORATION
Ort der Veröffentlichung:NEW YORK
Band:2015
Seitenbereich:S. 1-8
Datum16 Februar 2015
InstitutionenMedizin > Lehrstuhl für Neurochirurgie
Identifikationsnummer
WertTyp
10.1155/2015/124325DOI
Article ID 124325Andere
Stichwörter / KeywordsINTENSIVE-CARE-UNIT; ANEURYSMAL SUBARACHNOID HEMORRHAGE; SEVERE HEAD-INJURY; NEUROCRITICAL CARE; INTRACRANIAL-PRESSURE; MICRODIALYSIS;
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-313532
Dokumenten-ID31353

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