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Windowed multi taper correlation analysis of multimodal brain monitoring parameters
Faltermeier, Rupert, Bele, Sylvia, Proescholdt, Martin A. and Brawanski, Alexander (2015) Windowed multi taper correlation analysis of multimodal brain monitoring parameters. Computational and Mathematical Methods in Medicine 2015, pp. 1-8.Date of publication of this fulltext: 19 Feb 2015 13:07
Article
DOI to cite this document: 10.5283/epub.31353
Abstract
Although multimodal monitoring sets the standard in daily practice of neurocritical care, problem-oriented analysis tools to interpret the huge amount of data are lacking. Recently a mathematical model was presented that simulates the cerebral perfusion and oxygen supply in case of a severe head trauma, predicting the appearance of distinct correlations between arterial blood pressure and ...
Although multimodal monitoring sets the standard in daily practice of neurocritical care, problem-oriented analysis tools to interpret the huge amount of data are lacking. Recently a mathematical model was presented that simulates the cerebral perfusion and oxygen supply in case of a severe head trauma, predicting the appearance of distinct correlations between arterial blood pressure and intracranial pressure. In this study we present a set of mathematical tools that reliably detect the predicted correlations in data recorded at a neurocritical care unit. The time resolved correlations will be identified by a windowing technique combined with Fourier-based coherence calculations. The phasing of the data is detected by means of Hilbert phase difference within the above mentioned windows. A statistical testing method is introduced that allows tuning the parameters of the windowing method in such a way that a predefined accuracy is reached. With this method the data of fifteen patients were examined in which we found the predicted correlation in each patient. Additionally it could be shown that the occurrence of a distinct correlation parameter, called scp, represents a predictive value of high quality for the patients outcome.
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Details
| Item type | Article | ||||||
| Journal or Publication Title | Computational and Mathematical Methods in Medicine | ||||||
| Publisher: | HINDAWI PUBLISHING CORPORATION | ||||||
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| Place of Publication: | NEW YORK | ||||||
| Volume: | 2015 | ||||||
| Page Range: | pp. 1-8 | ||||||
| Date | 16 February 2015 | ||||||
| Institutions | Medicine > Lehrstuhl für Neurochirurgie | ||||||
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| Keywords | INTENSIVE-CARE-UNIT; ANEURYSMAL SUBARACHNOID HEMORRHAGE; SEVERE HEAD-INJURY; NEUROCRITICAL CARE; INTRACRANIAL-PRESSURE; MICRODIALYSIS; | ||||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||||
| Status | Published | ||||||
| Refereed | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg | Yes | ||||||
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-313532 | ||||||
| Item ID | 31353 |
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