A strategy is proposed for the design of low toxic, room temp. liq. low-melting mixts. (LMMs) which are entirely composed of natural materials. From literature it is well known that, in general, deep eutectic solvents based on choline chloride and dicarboxylic acids are LMMs, but not liqs. at room temp., with one exception: a 1:1 M mixt. of malonic acid and choline chloride. Therefore, the starting point of this study was the decrease of the m.p. of one of the components, namely the dicarboxylic acid, which is succinic, glutaric, or adipic acid. For this purpose, one of the two protons of the acidic group was exchanged by a bulky unsym. choline cation. The resulting ionic liqs. (ILs) were still solid at room temp., but have a reduced melting temp. compared with the corresponding acids. In the second step, mixts. of these ILs with choline chloride were prepd. It turned out that choline glutarate-choline chloride mixts. are liqs. at room temp. at compns. contg. 95-98 wt.% of choline glutarate. Finally, urea was added as another hydrogen bond donor. D., cond., and viscosity measurements were performed for all obtained mixts. Moreover, a Walden plot was drawn which indicates that all mixts. are liqs. with fully dissocd. ions moving independently. Therefore, they are considered as "good" ionic liqs. and, thus, for example they can be used to exchange more toxic or less biodegradable ILs in application processes. A brief outlook contg. application possibilities is given. It is demonstrated that choline dodecylsulfate is readily sol. in these mixts., forming aggregates in the LMM at temps. exceeding 55°C.