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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-315056
- DOI to cite this document:
- 10.5283/epub.31505
Abstract
Signal transducer and activator of transcription STAT5 is essential for the regulation of proliferation and survival genes. Its activity is tightly regulated through cytokine signaling and is often upregulated in cancer. We showed previously that the deacetylase inhibitor trichostatin A (TSA) inhibits STAT5-mediated transcription by preventing recruitment of the transcriptional machinery at a ...

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