Go to content
UR Home

Die Rolle des Transkriptionsfaktors ZBTB16 bei der osteogenen Differenzierung dentaler Follikelzellen

URN to cite this document:
urn:nbn:de:bvb:355-epub-315208
Felthaus, Oliver Heinrich
Date of publication of this fulltext: 26 Mar 2015 15:18


Abstract (German)

Dentale Follikelzellen (Dental Follicle Cells, DFCs) lassen sich durch Stimulation mit den Wachstumsfaktoren BMP2 (Bone Morphogenetic Protein 2) oder IGF2 (Insulin-like Growth Factor 2) sowie dem Glucocorticoid Dexamethason osteogen differenzieren. Während alle drei Induktoren geeignet sind, die Steigerung der ALP (Alkalische Phosphatase)-Aktivität und die Bildung einer mineralisierten Matrix zu ...

plus

Translation of the abstract (English)

Dental follicle cells (DFCs) can be differentiated into the osteogenic lineage by stimulation with growth factors BMP2 or IGF2 or the glucocorticoid dexamethasone. Treatment with either of theses induces an increased ALP activity and a mineralization, but upregulation of typical osteogenic marker genes like the transcription factor RUNX2 can be observed after treatment with BMP2 or IGF2, only. ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons