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Combinatorial Liquid-Phase Synthesis of [1,4]oxazepine-7-ones via the Baylis-Hillman Reaction

Räcker, Reinhard, Döring, Klaus and Reiser, Oliver (2000) Combinatorial Liquid-Phase Synthesis of [1,4]oxazepine-7-ones via the Baylis-Hillman Reaction. Journal of Organic Chemistry 65 (21), pp. 6932-6939.

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Other URL: http://dx.doi.org/10.102/jo0004916


A new method for the synthesis of [1,4]oxazepin-7-ones from readily available aldehydes and -amino alcohols was developed using the Baylis-Hillman reaction as the key step. To determine the scope and limitations of the method, a mixture library was synthesized from six aldehydes and six -amino alcohols on the soluble polymer support poly(ethylene glycol) 5000 monomethyl ether (MeOPEG) via split ...


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Item type:Article
Date:20 October 2000
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
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Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:316
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