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Treatment-emergent adverse events after infusion of adherent stem cells: the MiSOT-I score for solid organ transplantation

Dillmann, Johannes (2015) Treatment-emergent adverse events after infusion of adherent stem cells: the MiSOT-I score for solid organ transplantation. PhD, Universität Regensburg.

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Date of publication of this fulltext: 16 Apr 2015 10:36

Abstract (English)

Background: Cellular therapy after organ transplantation is emerging as an intriguing strategy to achieve dose reduction of classical immunosuppressive pharmacotherapy. Here, we introduce a new scoring system to assess treatment-emergent adverse events (TEAEs) of adherent stem cell therapies in the clinical setting of allogeneic liver transplantation (e.g. the MiSOT-I trial Eudract CT: ...

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Translation of the abstract (German)

Einleitung Es ist das Ziel dieser Studie, ein neu entwickeltes Bewertungssystem (MiSOT-I Score) zur Erfassung unerwünschter Wirkungen einer Therapie mit mesenchymaler Stammzelltherapie nach Lebertransplantation retrospektiv zu validieren. Dieser Score soll künftig im Rahmen einer Phase-I Studie der MiSOT Arbeitsgruppe (Mesenchymal Stem Cells in Solid Organ Transplantation) angewandt werden. ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:16 April 2015
Referee:Prof. Dr. Marc-H. Dahlke, PhD
Date of exam:10 April 2015
Institutions:Medicine > Lehrstuhl für Chirurgie
Keywords:adherent adult stem cells, mesenchymal stem cells, multipotent adult progenitor cells, solid organ transplantation, immunotherapy, scoring adverse events, phase I trial
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31626
Owner only: item control page

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