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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-316412
- DOI to cite this document:
- 10.5283/epub.31641
Abstract (English)
Aim: To evaluate whether and how the transcription factor early growth response gene 1 (EGR1) affects the osteogenic differentiation of dental stem cells. Methology: Dental stem cells from apical papilla (SCAPs) and from the dental follicle (DFCs) were transfected with EGR1 specific siRNA or EGR-1 expression plasmid. Gene regulation was verified at protein level by Western blotting. The ...
Translation of the abstract (German)
Fragestellung: Beeinflusst early growth response gene 1 (EGR1) die osteogene Differenzierung in dentalen Stammzellen und wenn ja, was sind die möglichen Mechanismen dahinter? Methodik: Dentale Stammzellen der apikalen Papille (SCAP) und dentale Follikelzellen (DFC) wurden mit einer EGR1-spezifischen siRNA oder einem EGR1-Expressionsplasmid transfiziert. Die Expression osteogener Markergene wurde ...