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EGR1 supports the osteogenic differentiation of dental stem cells

Preß, Thomas (2015) EGR1 supports the osteogenic differentiation of dental stem cells. PhD, Universität Regensburg.

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Date of publication of this fulltext: 20 Apr 2015 12:39

Abstract (English)

Aim: To evaluate whether and how the transcription factor early growth response gene 1 (EGR1) affects the osteogenic differentiation of dental stem cells. Methology: Dental stem cells from apical papilla (SCAPs) and from the dental follicle (DFCs) were transfected with EGR1 specific siRNA or EGR-1 expression plasmid. Gene regulation was verified at protein level by Western blotting. The ...

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Translation of the abstract (German)

Fragestellung: Beeinflusst early growth response gene 1 (EGR1) die osteogene Differenzierung in dentalen Stammzellen und wenn ja, was sind die möglichen Mechanismen dahinter? Methodik: Dentale Stammzellen der apikalen Papille (SCAP) und dentale Follikelzellen (DFC) wurden mit einer EGR1-spezifischen siRNA oder einem EGR1-Expressionsplasmid transfiziert. Die Expression osteogener Markergene wurde ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:20 April 2015
Referee:PD Dr. Christian Morsczeck
Date of exam:14 April 2015
Institutions:Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Keywords:Early growth response gene 1 (EGR1), stem cells from apical papilla (SCAPs), dental follicle precursor cells (DFCs), distal-less homeobox 3 (DLX3), bone morphogenetic protein 2 (BMP2)
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31641
Owner only: item control page

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