Urinary Biomarkers TIMP-2 and IGFBP7 Early Predict Acute Kidney Injury after Major Surgery

URN to cite this document:: urn:nbn:de:bvb:355-epub-317790
DOI to cite this document:: 10.5283/epub.31779

Göcze, Ivan ; Koch, Matthias ; Renner, Philipp ; Zeman, Florian ; Graf, Bernhard M. ; Dahlke, Marc H. ; Nerlich, Michael ; Schlitt, Hans-Jürgen ; Kellum, John A. ; Bein, Thomas

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Date of publication of this fulltext: 06 May 2015 09:37

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Abstract

Objective To assess the ability of the urinary biomarkers IGFBP7 (insulin-like growth factor-binding protein 7) and TIMP-2 (tissue inhibitor of metalloproteinase 2) to early predict acute kidney injury (AKI) in high-risk surgical patients. Introduction Postoperative AKI is associated with an increase in short and long-term mortality. Using IGFBP7 and TIMP-2 for early detection of cellular kidney ...