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Analysis of small RNA-Argonaute complexes in different organisms

Dueck, Anne (2015) Analysis of small RNA-Argonaute complexes in different organisms. PhD, Universität Regensburg.

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Date of publication of this fulltext: 29 May 2015 15:20

Abstract (English)

MicroRNAs (miRNAs) are small, non-coding RNAs of 20-24 nt in length. They are bound by members of the Argonaute protein family and play important roles in various processes including development, cellular homeostasis or response to external stimuli. Mis-regulations of miRNAs cause diseases such as cancers. In several chapters, this thesis describes miRNA profiles, miRNA and Argonaute protein ...


Translation of the abstract (German)

MicroRNAs (miRNAs) sind kleine, nicht-kodierende RNAs mit einer Länge von 20-24 Nukleotiden (nt). Sie werden von einem Mitglied der Argonaute Proteinfamilie gebunden und spielen in verschiedenen Prozessen wie Entwicklung, zelluläre Homöostase oder der Antwort auf externe Stimuli eine große Rolle. Fehl-Regulationen von miRNAs erzeugen Krankheiten wie z.B. Krebs. In dieser Dissertation werden in ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:29 May 2015
Referee:Prof. Dr. Gunter Meister
Date of exam:16 March 2015
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I
Keywords:miRNA, Argonaute, Volvox
Dewey Decimal Classification:500 Science > 570 Life sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31876
Owner only: item control page


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