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Analysis of small RNA-Argonaute complexes in different organisms

Dueck, Anne (2015) Analysis of small RNA-Argonaute complexes in different organisms. PhD, Universität Regensburg.

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Date of publication of this fulltext: 29 May 2015 15:20

Abstract (English)

MicroRNAs (miRNAs) are small, non-coding RNAs of 20-24 nt in length. They are bound by members of the Argonaute protein family and play important roles in various processes including development, cellular homeostasis or response to external stimuli. Mis-regulations of miRNAs cause diseases such as cancers. In several chapters, this thesis describes miRNA profiles, miRNA and Argonaute protein ...

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Translation of the abstract (German)

MicroRNAs (miRNAs) sind kleine, nicht-kodierende RNAs mit einer Länge von 20-24 Nukleotiden (nt). Sie werden von einem Mitglied der Argonaute Proteinfamilie gebunden und spielen in verschiedenen Prozessen wie Entwicklung, zelluläre Homöostase oder der Antwort auf externe Stimuli eine große Rolle. Fehl-Regulationen von miRNAs erzeugen Krankheiten wie z.B. Krebs. In dieser Dissertation werden in ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:29 May 2015
Referee:Prof. Dr. Gunter Meister
Date of exam:16 March 2015
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I
Keywords:miRNA, Argonaute, Volvox
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31876
Owner only: item control page

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