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Traceless stereoinduction for the enantiopure synthesis of substituted cyclopent-2-enones: Total synthesis of (-)-teuclatriol and (+)-orientalol-F

Arisetti, Nanaji (2016) Traceless stereoinduction for the enantiopure synthesis of substituted cyclopent-2-enones: Total synthesis of (-)-teuclatriol and (+)-orientalol-F. PhD, Universität Regensburg.

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Date of publication of this fulltext: 02 Jun 2016 11:00

Abstract (English)

Cyclopent-2-enone is one of the most important core structures in many bioactive prostaglandin derivatives and sesquiterpenes. Cyclopent-2-enone prostaglandin derivatives show anti-inflammatory and antiviral activity and inhibit NF-κB activation in human cell stimulated with tumor necrosis factor-α. Guaianes sesquiterpenes and pseudoguaianolides are widely obtained from many plants. These ...

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Translation of the abstract (German)

Cyclopent-2-enon stellt eine der wichtigsten Kernstrukturen in vielen bioaktiven Prostaglandin Deriviaten und Sesquiterpenen dar. Cyclopent-2-enon Prostaglandin Derivate wirken sowohl entzündungshemmend also auch antiviral und unterdrücken eine durch Tumornekrosefaktor-α stimulierte NF-κB Aktivierung in menschlichen Zellen. Guajan-Sesquiterpene und Pseudoguaianolide können aus einer Vielfalt an ...

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Export bibliographical data



Item type:Thesis of the University of Regensburg (PhD)
Date:1 June 2016
Referee:Prof. Dr. Oliver Reiser
Date of exam:26 May 2015
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Keywords:Cyclopent-2-enones, prostaglandins, TEI-9826, Schwartz reagent, guaiane sesquiterpenes, teuclatriol, orientalol-F, englerin-A, one-pot economy, pseudoguaianolides, metathesis
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31885
Owner only: item control page

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