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Statistical and experimental analysis of genetic and non-genetic markers associated with risk and progression of age-related macular degeneration (AMD)

Graßmann, Felix (2016) Statistical and experimental analysis of genetic and non-genetic markers associated with risk and progression of age-related macular degeneration (AMD). PhD, Universität Regensburg.

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Date of publication of this fulltext: 17 Aug 2016 12:16

Abstract (English)

Age-related macular degeneration (AMD) is a degenerative disease of the central retina and a leading cause of severe vision impairment in industrialized countries. AMD is a complex disease caused by genetic predisposition and environmental factors. Early stages of the disease usually do not lead to visual impairment. In contrast, the late stage forms of AMD can result in profound vision loss, ...

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Translation of the abstract (German)

Die altersabhängige Makuladegeneration (AMD) ist eine degenerative Erkrankung der zentralen Retina und eine der Hauptursachen von Erblindungen in höherem Alter. AMD ist eine komplexe Krankheit ausgelöst durch genetische und umweltbedingte Faktoren. Die Frühform der AMD führt in der Regel nicht zu Einschränkungen der Sehfähigkeit. Im Gegensatz dazu kann die Spätform der AMD zu einem starken ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:17 August 2016
Referee:Prof. Dr. Bernhard Weber and Prof. Dr. Iris Heid and Prof. Dr. Heike Bickeböller
Date of exam:31 July 2015
Institutions:Medicine > Lehrstuhl für Humangenetik
Keywords:AMD, Altersabhängige Makuladegeneration, age-related macula degeneration, genetics, Genetik, association, Assoziation, microRNA, circulating microRNA, risk prediction, Risikovorhersage, DAPL1, geographic atrophy, Geographische Atrophie, lesion growth, Wachstum der Läsionen
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32347
Owner only: item control page

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