Hennig, Robert, Ohlmann, Andreas, Staffel, Janina, Pollinger, Klaus, Haunberger, Alexandra, Breunig, Miriam, Schweda, Frank, Tamm, Ernst R. and Goepferich, Achim (2015) Multivalent nanoparticles bind the retinal and choroidal vasculature. Journal of Controlled Release 220 (Part A), pp. 265-274.
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Abstract
The angiotensin II receptor type 1 (AT1R), which is expressed in blood vessels of the posterior eye, is of paramount significance in the pathogenesis of severe ocular diseases such as diabetic retinopathy and age-related macular degeneration. However, small molecule angiotensin receptor blockers (ARBs) have not proven to be a significant therapeutic success. We report here on a nanoparticle ...
Export bibliographical data
| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 2015 | ||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich) | ||||
| Identification Number: |
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| Keywords: | Multivalency; EXP3174; Quantum dots; Age-related macular degeneration; Diabetic retinopathy; Angiotensin II | ||||
| Dewey Decimal Classification: | 600 Technology > 615 Pharmacy | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 32730 |
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