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Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

Grässel, Susanne, Muschter, Dominique, Schäfer, Nicole, Stangl, Hubert and Straub, Rainer H. (2015) Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis. PLoS ONE 2015 (10), e0139726.

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Date of publication of this fulltext: 26 Nov 2015 13:37

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Other URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139726


Abstract

Excessive synovial osteoclastogenesis is a hallmark of rheumatoid arthritis (RA). Concomitantly, local synovial changes comprise neuronal components of the peripheral sympathetic nervous system. Here, we wanted to analyze if collagen-induced arthritis (CIA) alters bone marrow-derived macrophage (BMM) osteoclastogenesis and osteoclast activity, and how sympathetic neurotransmitters participate in ...

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Item type:Article
Date:2 October 2015
Institutions:Medicine > Lehrstuhl für Orthopädie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0139726DOI
Article ID: e0139726Other
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32922
Owner only: item control page

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